Postdoc: Endocytosis, Signalling & Cancer Research

IEO - European Institute of Oncology; Lombardia; On-site; EUR 36,000 - 41,000; Full time

Benefits offered by this job

Job summary

IEO - European Institute of Oncology in Milan, Italy invites applications for a Postdoctoral Position in the Endocytosis, Signalling and Cancer Lab. The project focuses on using PetSign and StemPrintER signatures to improve prognostic stratification in breast cancer and identify FDA-approved drugs targeting these phenotypes.

Responsibilities include deriving PetSign and StemPrintER risk scores, benchmarking them against existing predictors, and validating related genes in BC cell lines;

Qualifications

• PhD in Cancer Biology, Cell Biology, Molecular Biology, Systems Medicine or related life sciences.
• Strong experience in mammalian cell culture and functional assays.
• Experience in RNAseq, scRNAseq and bioinformatics.
• A genuine interest in translational cancer research.

Responsibilities

• Derivation of a PetSign risk score (PRS) and a StemPrintER risk score (SPRS).
• Benchmarking PRS and SPRS vs. available BC predictors.
• Molecular and phenotypic validation in BC lines of PetSign and StemPrintER genes.

Skills

Mammalian cell culture

Functional assays

RNAseq

scRNAseq

Bioinformatics

Translational cancer research

Education

PhD in Cancer Biology, Cell Biology, Molecular Biology, Systems Medicine or related life sciences

Job description

IEO - European Institute of Oncology in Milan, Italy invites applications for a Postdoctoral Position in the Endocytosis, Signalling and Cancer Lab. The project focuses on using PetSign and StemPrintER signatures to improve prognostic stratification in breast cancer and identify FDA-approved drugs targeting these phenotypes.

Responsibilities include deriving PetSign and StemPrintER risk scores, benchmarking them against existing predictors, and validating related genes in BC cell lines;