MSCA Postdoctoral Fellowship on Innate immunity and cancer

euraxess.ec.europa.eu - Jobboard; Italia; In loco; EUR 30.000 - 50.000; Tempo pieno

Descrizione del lavoro

L'Université de Vérone recherche des candidats pour une bourse postdoctorale Marie Skłodowska-Curie axée sur l'immunité innée et le cancer. Les candidats retenus bénéficieront d'un soutien académique et administratif pour la préparation des propositions. Ce poste offre l'opportunité de travailler sur des projets innovants en biologie cellulaire et moléculaire.

Competenze

• Avoir un doctorat avant la date limite de l'appel (10 septembre 2025).
• Jusqu'à 8 ans d'expérience en recherche après le doctorat.
• Citoyenneté d'un État membre de l'UE ou d'un pays associé.

Mansioni

• Identifier et caractériser les précurseurs de neutrophiles et de monocytes.
• Étudier les cellules immunitaires dans le contexte du cancer.
• Caractériser l'origine et les voies de différenciation des monocytes dans les tumeurs.

Conoscenze

Fluency in English

Teamwork attitude

Organizational skills

Ability to work in a multidisciplinary environment

Formazione

PhD

Descrizione del lavoro

Organisation / Company: Università degli Studi di Verona

Department: Department of Medicine, Institute of General Pathology

Is the Hosting related to staff position within a Research Infrastructure? No

Prof. Marco A. Cassatella invites scholars to present expressions of interest in applying jointly with the Department of Medicine - Institute of General Pathology at the University of Verona for a Marie Skłodowska-Curie Postdoctoral Fellowship (MSCA-PF) on Innate immunity and cancer.

The lab offers several ongoing projects:

1. Identification and molecular characterization of very immature CD34+/- neutrophil and monocyte progenitors in healthy human donors and cancer patients;
2. To shed definitive light on the phenotypic, transcriptomic, and functional features of human monocytic myeloid-derived suppressor cells (M-MDSCs) by investigating CD14+HLA-DRlow/-CXCR1- and CD14+HLA-DRlow/-CXCR1+ monocyte subtypes in different types of cancer patients and healthy donors. This includes understanding whether M-MDSCs are reprogrammed mature monocytes or a different cell type;
3. Characterization of the fate of slan+ monocytes in human tumors, defining their origin and differentiation pathways using bioinformatics. These projects require expertise in cell and molecular biology/biochemistry techniques, which are available in the lab and can be learned.

Hosting Research Group / Supervisor

We are looking for applicants for a Marie Skłodowska-Curie Postdoctoral Fellowship to be presented with our Centre / Department as the main host institution.

Prof. Cassatella’s research focuses on understanding the molecular mechanisms regulating innate immune cells in the context of innate immunity and cancer. His group has contributed significantly to the understanding of neutrophil functions, their role in angiogenesis, and their impact on tumor biology. Recent efforts include studying human slan+ monocytes in tumors and identifying novel neutrophil progenitors, with ongoing characterization of their roles in cancer.

Selected candidates will receive academic and administrative support from the Centre / Department and the University of Verona Grant Office for proposal preparation.

Eligibility

Candidates must meet the criteria of the 2025 MSCA Postdoctoral Fellowship call:

• Having a PhD by the call deadline (September 10, 2025)
• Up to 8 years of research experience after PhD
• Citizenship of an EU Member State or an Associated Country, or long-term residence in Europe (for Global Fellowships)
• For European Fellowships: Not having resided or carried out main activity in Italy for more than 12 months in the 36 months prior to the call deadline
• For Global Fellowships: Not having resided or carried out main activity in the host country for more than 12 months in the 36 months prior to the call deadline

Additional requirements include fluency in English, teamwork attitude, organizational skills, and ability to work in a multidisciplinary environment.

• A short CV including personal data (name, date of birth, present position, and a referee's name who has agreed to send a reference letter)
• One reference letter should be sent by the referee to the same address.