Mrna/Lnp Process Development Scientist

Buscojobs; Lombardia; In loco; EUR 50.000 - 70.000; Tempo pieno

Descrizione del lavoro

A leading company seeks an mRNA / LNP Process Development Scientist in Monza. The role involves leading cross-functional teams in biopharmaceutical projects, developing processes for mRNA molecules, and improving departmental technologies. A Master’s or PhD in a related field with substantial industry experience is required.

Competenze

• 5+ years in the Biopharmaceutical industry preferred.
• Experience with HPLC / FPLC, TFF techniques.
• Post-doctoral or industrial experience desirable.

Mansioni

• Lead problem-solving in multi-disciplinary teams.
• Design experimental plans and analyze data.
• Develop customer relationships through technical interactions.
• Provide solutions for process risks and problems.

Conoscenze

Experience with biomolecule purification techniques

Knowledge of technology transfer

Implementation of DoE studies

Understanding in vitro transcription parameters

Experience in manufacturing large mRNA molecules

Understanding the mRNA-LNP encapsulation process

Formazione

Master’s Degree in life science or equivalent

PhD in Biochemistry or related fields

Descrizione del lavoro

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mRNA / LNP Process Development Scientist, Monza

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Client :

Thermo Fisher Scientific

Location : Job Category :

Other

EU work permit required :

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Job Reference : 756a86b263cd

Job Views : Posted :

14.06.2025

Expiry Date : 29.07.2025

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Job Description :

• Participate in multi-disciplinary matrix teams on sophisticated projects and lead problem-solving and lessons-learned activities.
• Design and implement experimental plans, analyze in-process data and write and review high-quality reports.
• Develop strong customer relationships through technical interactions.
• Lead activities in the area of mRNA / LNP expertise.
• Provide solutions to identify process risks, issues, and problems.
• Contribute to improving departmental processes and implementing innovative technologies.
• Demonstrate flexibility to support activities within the department.

Qualifications

A Master’s Degree in life science, Chemical, Biological, or Process Engineering, or equivalent experience, with 5+ years of confirmed experience in the Biopharmaceutical industry, preferably in a PD role. Alternatively, a PhD in Biochemistry, Chemistry, Chemical Engineering, Biological Engineering, or related scientific subject areas, or equivalent experience, with +2 years of relevant post-doctoral or industrial experience.

Key Requirements

• Experience with biomolecule purification techniques such as HPLC / FPLC chromatography (including affinity, ion exchange, hydrophobic interactions, and size exclusion), tangential flow filtration (TFF), and other filtration techniques.
• Knowledge of technology transfer and GMP manufacturing.
• Implementation of DoE studies & high-throughput screening for purification processes.
• Understanding in vitro transcription (IVT) critical process parameters, reaction optimization, and scale-up.
• Experience in manufacturing large mRNA molecules, including self-amplifying and circular RNAs.
• Understanding the mRNA-LNP encapsulation process scale-up and execution of relevant associated analytical methods.
• Proven track record of efficiently working in a fast-paced and multifaceted environment.

Thermo Fisher Scientific is an Equal Opportunity Employer.

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