Manufacturing Sciences: Formulation Scientist – Lyophilization

Thermo Fisher; Italia; In loco; EUR 42.000 - 64.000; Tempo pieno

Descrizione del lavoro

Thermo Fisher Scientific is seeking a Manufacturing Sciences Scientist I to support manufacturing operations by developing, optimizing, and implementing production processes for diagnostics, research, and therapeutic applications.

The role involves cross-functional collaboration with Analytical Development, Quality Assurance and Clinical Operations to ensure quality and compliance, while contributing to process improvements and patient care.

Competenze

• Bachelor's degree required; no prior GMP environment experience required.
• Fields of study: Chemistry, Biochemistry, Chemical Engineering, Biotechnology or related scientific field.
• Proficiency in standard laboratory techniques and equipment operation.
• Working knowledge of GMP, GDP and other regulatory requirements.
• Strong technical writing for SOPs, batch records and investigation reports.
• Proficiency with Microsoft Office and laboratory information systems.
• Strong analytical and problem-solving abilities.
• Effective communication and ability to work collaboratively in teams.
• Ability to work varied schedules including potential overtime.
• Physical ability to lift up to 35 pounds in lab/manufacturing environments.
• English language proficiency required; additional languages beneficial.

Mansioni

• Formulation Design: Develop stable liquid, lyophilized, and parenteral formulations for small molecules and biologics.
• Pre-Formulation Screening: Conduct physicochemical characterization, including pH-solubility, pKa, excipient compatibility, and forced degradation studies.
• Process Optimization: Design and execute robust freeze-drying (lyophilization) cycles.
• Scale-Up & Tech Transfer: Lead transfer of formulation processes from bench to pilot and GMP manufacturing facilities.
• Cross-Functional Collaboration: Collaborate with Analytical Development, Quality Assurance, and Clinical Operations to meet project timelines.

Conoscenze

Analytical skills

Technical writing

Laboratory techniques

Regulatory knowledge

Communication

Team collaboration

Problem-solving

Microsoft Office

Formazione

Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, Biotechnology or related scientific field

Strumenti

Laboratory information systems

Descrizione del lavoro

Thermo Fisher Scientific is seeking a Manufacturing Sciences Scientist I to support manufacturing operations by developing, optimizing, and implementing production processes for diagnostics, research, and therapeutic applications.

The role involves cross-functional collaboration with Analytical Development, Quality Assurance and Clinical Operations to ensure quality and compliance, while contributing to process improvements and patient care.