Doctoral Candidate - 3D Genome Dynamics of RNA Factory Assembly in Human Cardiomyocyte Programming

European Commission; Italia; In loco; EUR 12.000 - 18.000; Tempo pieno

Descrizione del lavoro

A leading research institution in Italy is offering a fully funded 3-year PhD position in Molecular Biotechnology. The role focuses on innovative research integrating biochemistry and genomics to address congenital heart defects. Ideal candidates will hold a Master's degree and possess research experience in relevant fields. This position provides high-level mentorship, advanced training, and international collaboration opportunities, with flexible work in culturally vibrant Turin.

Servizi

High-level mentoring

Access to advanced training

International exchange opportunities

Competenze

• MSc (or equivalent) in biotechnology, molecular biology, or related field.
• Prior research experience in experimental work and data analyses.
• Familiarity with pluripotent stem cells, 3D chromatin biology, or cardiac development.

Mansioni

• Conduct research on cardiac transcription factors and cell fate engineering.
• Collaborate internationally to study heart defects.

Conoscenze

Hybrid wet and dry lab skills

Strong writing skills

Organizational skills

Team collaboration skills

Formazione

Master's degree in biotechnology

Descrizione del lavoro

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University of Turin - Molecular Biotechnology Center

Organisation/Company University of Turin - Molecular Biotechnology Center Department Department of Molecular Biotechnology and Health Sciences Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Italy Application Deadline 27 Aug 2025 - 13:00 (Europe/Rome) Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 15 Nov 2025 Is the job funded through the EU Research Framework Programme? Horizon Europe - ERC Reference Number 101076026 Is the Job related to staff position within a Research Infrastructure? No

This fully funded position is part of theCell & Gene Therapy Curriculumof the national PhD program in Science and Technology for Advanced Therapies (STAT) —a highly selective initiative backed by Fondazione Telethon, among others, built to match top-tier European PhD programs.

The project is part of the European Research Council Starting Grant “TRANS-3” and integrates cutting-edge nucleic acid biochemistry, functional genomics, and bioinformatics (PMIDs: 39574693 , 39322282 ; doi: 10.2139/ssrn.4854180 ), applied to study master cardiac transcription factors in 3D genome control of hiPSC models. The dual goal is to improve our understanding of congenital heart defects while learning how to engineer cell fate for cardiac cell therapies. International collaborations include theUniversity of Washington.

You have:

• MSc (or equivalent) in biotechnology, molecular biology, or a closely related discipline
• Passion for fundamental questions with a clear translational potential
• Motivation to grow as an independent scientist with hybrid wet and dry lab skills

And ideally have:

• Prior research experience in both experimental work and data analyses
• Familiarity with pluripotent stem cells, 3D chromatin biology, and/or cardiac development
• Strong writing, organizational, and team collaboration skills

We offer:

• An international and highly collaborative workplace in scenic, affordable, and culturally vibrant Turin
• A fully funded 3-year PhD position, with top-up support available for exceptional candidates
• High-level mentoring, access to advanced training, and international exchange opportunities
• MSc (or equivalent) in biotechnology, molecular biology, or a closely related discipline
• Passion for fundamental questions with a clear translational potential
• Motivation to grow as an independent scientist with hybrid wet and dry lab skills

Specific Requirements

• Prior research experience in both experimental work and data analyses
• Familiarity with pluripotent stem cells, 3D chromatin biology, and/or cardiac development
• Strong writing, organizational, and team collaboration skills

Languages ENGLISH Level Excellent

Languages ITALIAN

Research Field Biological sciences » Biology Years of Research Experience 1 - 4

Additional Information

• An international and highly collaborative workplace in scenic, affordable, and culturally vibrant Turin
• A fully funded 3-year PhD position, with top-up support available for exceptional candidates
• High-level mentoring, access to advanced training, and international exchange opportunities

Eligibility criteria

Applications are welcome from all qualified candidates, regardless of age or nationality. Eligible candidates must
hold the following academic qualifications:
a) Master’s degree (Laurea Magistrale or Laurea Specialistica or Laurea Vecchio Ordinamento);
b) Analogous academic qualification awarded abroad that is comparable to an Italian master’s degree, in
terms of duration and study content, and recognized by the Selection Board as suitable for application
to the course.
Applications from candidates who are still to graduate will be considered pending. The academic qualification
required for admission to the PhD programs must be obtained within the start date of the course.

Selection process

Selection will be based on an assessment of the qualifications listed in the “Qualification Assessment” section followed by an interview. The Selection Board will award a score from 1 to 100.

1. Qualification Assessment: The Selection Board will assess the applicants’ scientific qualifications and allocate an overall score up to a maximum of 60 points. Applicants who receive a score of at least 40 will be invited to attend an interview. The Selection Board will award scores based on:

• CV, academic qualifications and references (Required documents b, c, d, h): up to a maximum of 25 points;
• Research Proposal and Letter of Purpose (Required documents f and g): up to a maximum of 35 points.

At this stage candidates may already be determined non-eligible for one or more of the selected scholarships.

2. Interview: interviews will be conducted in English through platform and will focus on the applicant’s scientific background, Research Proposal, as well as the candidate's motivations. It will also include a discussion of a scientific paper on a topic relevant to the chosen CU, which will be provided by the Selection Board before the interview. At their discretion, candidates may also present the above using the screen sharing option within Teams (maximum of 6 slides).

3. The Selection Board can invite a proven expert for each research topic to participate in the interview. This expert could be a member of the Academic Board. The Selection Board will determine a score for the interview up to a maximum of 40 points. A minimum of 25 points is required to continue the process. During the interview, the Selection Board will verify that the candidate has the necessary knowledge and skills for attending the doctoral course and will proceed to evaluate the eligibility of the candidate for the research topics selected.