Development, validation and application of LC-MS/MS and UHPLC-MS/MS methods for steroid profiling within the 11β-HSD system

Italian Ministry of Education, University and Research; Italia; On-site; EUR 45,000 - 65,000; Full time

Job summary

Sapienza University of Rome invites applications for a research position supporting the FIS2-funded project on steroid profiling using LC-MS/MS and UHPLC-MS/MS. The appointee will develop, optimise, validate and apply analytical methods, contribute to sample preparation and data interpretation within human matrices and experimental models.

The role emphasizes analytical quality control, data reporting, and collaboration with a multidisciplinary team in Italy, contributing to high-impact results

Qualifications

• Develop, optimise, validate and apply LC-MS/MS and UHPLC-MS/MS methods for targeted steroid profiling.
• Contribute to sample preparation and analytical quality control.
• Interpret steroidomic data within the project framework.

Responsibilities

• Develop and validate steroid profiling methods.
• Analyze biological samples and report results.
• Ensure quality control of analytical data.

Skills

LC-MS/MS

UHPLC-MS/MS

steroid profiling

sample preparation

data interpretation

Tools

Mass spectrometry

Job description

Organisation/Company Università Sapienza Dipartimento di Medicina sperimentale Research Field Medical sciences » Medicine Researcher Profile Recognised Researcher (R2) Leading Researcher (R4) First Stage Researcher (R1) Established Researcher (R3) Application Deadline 12 Nov 2026 - 23:59 (UTC) Country Italy Type of Contract To be defined Job Status Not Applicable Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The research assignment will support the activities of the FIS2-funded project "Reshaping The Landscape of the 11 beta HSD System In Androgen Metabolism Kinetics", project code FIS-2023-02063, CUP B53C25001010001. The activity will focus on the development, optimisation, validation and application of LC-MS/MS and UHPLC-MS/MS methods for targeted steroid profiling in human biological matrices and experimental models, with particular reference to glucocorticoids, classical and 11-oxygenated androgens, cortisol, cortisone and related metabolites. The appointee will contribute to sample preparation, analytical quality control, quantitative analysis and interpretation of steroidomic data generated within the project

• Italy

Eligibility of fellows: country/ies of residence:

• OTHER

Eligibility of fellows: nationality/ies: