Associate Scientist, CMC Analytical Development

ZipRecruiter; Verona; In loco; USD 75.000 - 90.000; Tempo pieno

Descrizione del lavoro

An innovative biopharmaceutical company is seeking a dedicated Associate Scientist III to join their Analytical Development team. This exciting role involves supporting method development and validation for drug substances, conducting testing for GLP toxicology studies, and ensuring compliance with cGMP policies. The ideal candidate will have a strong background in chemistry, analytical techniques, and a passion for contributing to groundbreaking therapies. Join a team of nimble, science-driven innovators committed to delivering new treatments to patients in need. This is a fantastic opportunity to make a significant impact in the biopharmaceutical field.

Servizi

Competitive Salaries

Excellent Benefits

Authorization to Work in the US

Competenze

• 4+ years of experience in a chemistry laboratory setting.
• Familiarity with cGMP policies and analytical instrumentation.

Mansioni

• Support method development and validation for new drug substances.
• Perform testing of samples for batch release and stability studies.
• Write analytical test methods, protocols, and SOPs.

Conoscenze

Analytical Techniques (HPLC, GC, FTIR, UV/Vis, LC/MS, KF)

Data Analysis

Attention to Detail

Teamwork Skills

Formazione

BS or M.S. in Chemistry

Strumenti

Analytical Instruments

Descrizione del lavoro

Job Description

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical-stage biopharmaceutical company that develops medicines to treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a natural mechanism in living cells that inhibits the expression of specific genes, affecting the production of particular proteins. Arrowhead's RNAi-based therapeutics leverage this pathway to develop innovative treatments.

Arrowhead focuses on diseases with a genetic basis, often characterized by the overproduction of proteins involved in disease processes. Our versatile RNAi technologies enable us to address conditions across various therapeutic areas, including those not accessible by small molecules and biologics. We are leading the field in applying RNAi to treat diseases beyond the liver, with clinical pipeline targets in the liver and lung, and a promising pipeline of preclinical candidates.

Our corporate headquarters are in Pasadena, CA, with research and development teams in Madison, WI, and San Diego, CA. Our employees are nimble, science-driven innovators collaborating to bring new therapies to patients in need.

The Position

This role is part of the Analytical Development (AD) group within the CMC Manufacturing organization. The Associate Scientist III will support method development and validation activities for new drug substances and drug products. The position will also contribute to testing for GLP toxicology studies, cGMP clinical trial material release, and stability studies. The role reports to AD management.

Responsibilities

• Adhere to cGMP policies, procedures, and relevant SOPs
• Provide accurate analytical results supporting new and ongoing projects
• Meet project timelines and deliverables independently
• Perform testing of samples for batch release and stability studies
• Perform analytical techniques such as HPLC, GC, FTIR, UV/Vis, LC/MS, KF, etc.
• Assist in designing and initiating development of analytical methods and improving existing ones for all stages of drug development
• Handle, analyze, and characterize chemicals, pharmaceuticals, and related organic molecules
• Evaluate and interpret scientific data, providing significance
• Design and execute non-routine experiments independently
• Analyze data, interpret results, and propose follow-up actions
• Compile data tables, certificates of analysis, and develop stability reports
• Write analytical test methods, protocols, and SOPs
• Calibrate, maintain, and troubleshoot analytical equipment
• Perform other duties as assigned

Requirements

• BS or M.S. in Chemistry or related field
• At least 4 years of experience in a chemistry laboratory setting
• Familiarity with analytical instrumentation, test methodology/validation, data acquisition systems, and cGMP policies
• Ability to analyze data/results, interpret experiments, and propose follow-up
• Strong attention to detail
• Teamwork skills

Salary range in Wisconsin: $75,000—$90,000 USD

Arrowhead offers competitive salaries and excellent benefits. All applicants must have authorization to work in the US.

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