R&D API fermentation

Biocon; Bengaluru; On-site; INR 600,000 - 950,000; Full time

Job summary

Biocon in Bengaluru requires a Bioprocess Engineer to design and execute experiments for strain screening, media engineering and process optimization. You will work with bioreactors across batch, fed-batch, continuous and perfusion modes to drive improved production strains.

The role includes identifying critical process parameters, developing feeding strategies, and performing classical strain improvements, with cell bank preparation and QC transfer support.

Qualifications

• Masters degree in Bioprocess Engineering or Biotechnology.
• 2–3 years of industrial experience.
• Experience with strain screening and media engineering is preferred.

Responsibilities

• Design and execution of experiments for strain screening, media engineering and process optimization.
• Operate bioreactors/fermenters for batch, fed-batch, continuous and perfusion processes.
• Identify critical process parameters and devise feeding strategies to enhance productivity.
• Perform strain improvement via classical methods and selection.
• Prepare cell banks and support QC transfer; maintain lab records.
• Collaborate with CFTs for timely execution and scale-up.
• Develop SOPs, EOPs and maintain quality records.

Skills

Molecular biology

Genome editing

Data analysis

Experiment design

Process optimization

Education

MSc/MTech in Bioprocess Engineering or Biotechnology

Tools

Bioreactors

Fermentation

Omics data analysis

Job description

Engineer and optimize microbial strains using molecular biology, genome editing, strain improvement, and data-driven approaches to develop high-performing and stable production strains.

Key Responsibilities:

• Design and execution of experiments for strain screening, media engineering and process optimization.
• Bioreactors/fermenters handling on different processes (Batch, fed-batch, Continous and perfusion)
• Indentify the critical process parameters and devise optimal feeding strategies for the enhanced prductivites in the assigned projects
• Perform strain improvement via classical methods (mutation, selection, adaptation).
• Mutants screening for the improved productivity, Prepare cell bank and maintain for QC transfer Samples prepartion of omics studies, respective data anlysis.
• Document experimental data and maintain lab records as per compliance standards.
• Work in collaboration with CFTs for timely execution of the projects and process scale-up.
• Preparation of Standard operating procedures (SOPs), Equipemt operating procedures (EOPs) and timely generation and maintenace of the quality records
• Preparation of process protocls for the pilot plant batches, compilation and analysis of the data from the experiments for better understanding and planning the scale-up activites at the manufacturing site
• Preparation and review of procvess technical report, development report, and MFR on sucessful completion of the Project
• Support to the production team in closing the CAPA, OOS, OOT and deviations
• Ensure compliance with biosafety and regulatory guidelines.

Minimum Requirements :

• Masters Degree (MSc, MTech) in Bioprocess Engineering, Biotechnology with a ninimum of 2-3 Years of industrial experience