Executive-API R&D Synthesis with Growing Russia based Pharma

Best Fit Recruitment Rider; Navi Mumbai; On-site; INR 1,200,000 - 2,400,000; Full time

Job summary

BEST-FIT Recruitment Riders is seeking an experienced Executive-API R&D Synthesis for its client in Navi Mumbai. You will invent non-infringing, cost-effective synthetic pathways to produce APIs from lab scale to production, focusing on API R&D, scale-up, and technology transfer.

Candidates should have 4 to 7 years in API/Intermediate Process Development, strong organic synthesis skills, and familiarity with HPLC/GC/MS/NMR.

Qualifications

• M.Sc in Chemistry/Organic Chemistry/Pharmaceutical Chemistry with 4–7 years experience in API or bulk drug development.
• Experience in API/intermediate process development, R&D or process chemistry within pharma.
• Strong practical knowledge of organic synthesis, reaction chemistry, purification and process development.

Responsibilities

• Conduct lab-scale reactions for API development and optimize synthetic routes.
• Perform reaction monitoring, work-up, purification and isolation of products.
• Study parameters like temperature, time, solvent, catalyst and reagents to optimize processes.
• Support scale-up and technology transfer from R&D to production.
• Coordinate with analytical teams for testing and characterisation (HPLC/GC/MS/NMR).
• Prepare experimental/process development reports and ensure documentation accuracy.

Skills

Organic synthesis

Reaction chemistry

Purification

Process development

Analytical data interpretation

Education

M.Sc in Chemistry/Organic Chemistry/Pharmaceutical Chemistry

Tools

HPLC

GC

MS

NMR

Job description

Greetings! & very warm welcome to BEST-FIT Recruitment Riders,

We are BEST-FIT Recruitment Riders feel immense pleasure to search and provide you with better carrier opportunities to aid you in achieving your aspirations. BEST-FIT Recruitment Rider is a highly specialized Recruitment & Executive Search Partner for Pharmaceutical, Biotech, CRO, Chemicals, Medical Devices & Turnkey Pharma Projects Engineering-Construction Design Sectors. We are searching & recruiting highly qualified professionals for Middle-Senior-Upper-Management and Executive jobs. (Eg: Managers, VP, President, CFO & CEO). Also offering customized recruitment services by Headhunting & Executive Search for Middle & Top management level professionals according to clients specific needs. We are BEST-FIT Recruitment Riders do exactly what our name tells. To know more about us please visit our website: www.bestfitrecruitment.co.in

We would like to inform you that presently we have professional career opportunity matching to your profile with one of our esteemed client.

Please see the following position summary:

• Client Name: Growing Russia based Pharma
• Position: Executive-API R&D Synthesis
• Department: API R&D
• Location: Navi Mumbai

Role Objective:

Invent non-infringing, cost-effective, and safe synthetic pathways to create active pharmaceutical ingredients from lab scale to commercial production.

Job Profile:

Process Synthesis & Development:

• Conduct laboratory-scale chemical reactions for API and intermediate development.
• Develop, evaluate and optimize synthetic routes for new and existing molecules.
• Perform reaction monitoring, work-up, purification and isolation of products.
• Study reaction parameters such as temperature, time, solvent, catalyst and reagent quantities.
• Identify suitable and commercially feasible synthetic processes.

Process Optimization & Troubleshooting:

• Optimize chemical processes to improve yield, purity, reproducibility and process efficiency.
• Identify and troubleshoot issues related to reaction, impurity formation, crystallization and purification.
• Conduct experiments to understand and minimize process-related impurities.
• Support development of robust and scalable processes for commercial manufacturing.

Scale-Up & Technology Transfer:

• Help transition chemical processes from small laboratory setups to pilot plants or large-scale production.
• Support scale-up of laboratory processes to pilot and manufacturing scale.
• Assist in preparing process descriptions, batch procedures and scale-up documents.
• Participate in technology transfer activities from R&D to production.
• Provide technical support during pilot and commercial batches and resolve process-related issues.

Analytical Testing & Data Interpretation

• Possess basic working knowledge of analytical techniques such as HPLC, GC, MS and NMR.
• Review and interpret analytical results to assess product purity, impurities and reaction completion.
• Coordinate with analytical teams for testing and characterization of API/intermediate samples.
• Maintain proper records of analytical observations and experimental results.

Documentation & Compliance:

• Documentation & Regulatory Compliance
• Maintain accurate and timely documentation of daily experiments, observations and results.
• Prepare experimental reports, process development reports and supporting technical documents.
• Follow applicable GMP, safety and laboratory procedures during development activities.
• Support preparation and compilation of technical information required for regulatory submissions, including DMF-related documentation.
• Ensure proper traceability and data integrity of experimental and development records.

Safety & Good Laboratory Practices:

• Follow laboratory safety procedures while handling chemicals, reactions and laboratory equipment.
• Ensure proper handling, storage and disposal of chemicals and laboratory waste.
• Maintain a clean, organized and compliant laboratory environment.
• Follow GLP/GMP principles and company quality systems applicable to R&D activities.

Desired Profile:

• M.Sc (Chemistry / Organic Chemistry / Pharmaceutical Chemistry) with 4 to 7 years experience in R&D experience in bulk drug or API manufacturing environments.
• Relevant experience in API / Intermediate Process Development, R&D or Process Chemistry within the pharmaceutical industry.
• Strong practical knowledge of organic synthesis, reaction chemistry, purification and process development.
• Hands-on experience in laboratory-scale reactions, reaction optimization and impurity control.
• Good understanding of process scale-up, technology transfer and manufacturing process troubleshooting.
• Basic knowledge of analytical techniques including HPLC, GC, MS and NMR, with the ability to understand and interpret analytical results.
• Ability to analyse experimental data and make appropriate technical decisions based on observations and results.
• Good understanding of GMP, GLP, laboratory safety and chemical handling practices.
• Experience in preparing experimental records, process development reports, technical reports and regulatory documentation/DMF-related data.
• Deep knowledge of organic synthesis, lab safety (EHS guidelines), analytical data interpretation, and process optimization.
• Should have basic understanding and result interpterion knowledge about instruments like HPLC, GC, MS, and NMR to check product purity.
• Knowledge about technical development reports, safety protocols, and regulatory documents like Drug Master Files (DMF) while following Good Manufacturing Practices (GMP).
• Good documentation, report-writing and communication skills.
• Strong problem-solving, analytical and experimental skills with a result-oriented approach.
• Ability to work independently as well as effectively coordinate with Analytical, Production, Quality and Regulatory teams.