Senior Scientist: Process Chemistry & Tech Transfer

AstraZeneca; Dublin; On-site; EUR 70,000 - 110,000; Full time

Job summary

AstraZeneca plc in Dublin is seeking a Senior Scientist (Chemistry) to contribute to transfer, maintain and optimise supply for AstraZeneca products. You will drive process improvements using traditional and cutting-edge technologies, and provide hands-on experimentation and modelling support at our Dublin site.

You will contribute to CMC sections of regulatory submissions and respond to queries over the product lifecycle, with a focus on scale-up/down, process robustness, and cGMP compliance.

Qualifications

• BSc/PhD in a relevant discipline with pharma R&D or manufacturing experience.
• Expert understanding of practical synthetic organic chemistry in lab and production.
• Experience with Tech Transfer of Drug Substance processes.
• Experience scaling up and scaling down processes in pharma.
• Understanding of drug development from discovery to launch.
• Knowledge of SHE and cGMP principles and management.
• Strong communication and influence across interfaces and teams.
• Problem solving with deep technical skills and data-driven approach.
• Proficiency in statistics to understand data.

Responsibilities

• Support transfer, maintain and optimise supply for one or more AstraZeneca products.
• Identify, develop and implement process improvements using existing and cutting-edge technologies.
• Provide expert input through laboratory experiments, in-silico modelling and direct manufacturing support at the Dublin site.
• Contribute to CMC components of regulatory submissions and responses over the product lifecycle.

Skills

Organic synthesis

Tech Transfer

Scale-up/Scale-down

CMC regulatory

GMP/cGMP

Statistical analysis

Education

BSc/PhD in chemistry

Job description

AstraZeneca plc in Dublin is seeking a Senior Scientist (Chemistry) to contribute to transfer, maintain and optimise supply for AstraZeneca products. You will drive process improvements using traditional and cutting-edge technologies, and provide hands-on experimentation and modelling support at our Dublin site.

You will contribute to CMC sections of regulatory submissions and respond to queries over the product lifecycle, with a focus on scale-up/down, process robustness, and cGMP compliance.