Senior Scientist (Chemistry) – Tech Transfer & Process

AstraZeneca; Blanchardstown; On-site; EUR 70,000 - 90,000; Full time

Job summary

AstraZeneca plc in Dublin is seeking a Senior Scientist (Chemistry) to support the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements using existing and cutting-edge technologies, and provide expert input through laboratory experimentation and in-silico modelling.

The role involves direct manufacturing support at the AZ API site in Dublin and contributing to CMC sections

Qualifications

• PhD or MSc in a relevant discipline with pharma R&D or manufacturing experience.
• Expertise in practical synthetic organic chemistry from lab to manufacture.
• Experience in Tech Transfer of small molecule drug substance processes.
• Experience handling scale-up and scale-down of processes.
• Strong understanding of drug development from discovery to launch.
• Solid knowledge of SHE and cGMP principles.
• Excellent communication and strategic influencing skills.
• Proven problem solver with deep technical skills.
• Proficiency in statistics to interpret data.

Responsibilities

• Support the technical contribution to transfer, maintain and optimise supply for AstraZeneca commercial products.
• Identify, develop and implement process improvements using existing and cutting-edge technologies.
• Provide expert technical input through laboratory experiments, in-silico modelling, and direct manufacturing support at our internal AZ API manufacturing site in Dublin.
• Contribute to the CMC components of regulatory submissions and preparation of successful query responses over the commercial life of a product.

Skills

Synthetic organic chemistry

Tech Transfer

Scale-up / scale-down

Regulatory input (CMC)

Statistics

Cross-functional collaboration

Problem solving

Communication

Data interpretation

Education

BSc/PhD in a relevant discipline

Job description

AstraZeneca plc in Dublin is seeking a Senior Scientist (Chemistry) to support the technical contribution to transfer, maintain and optimise supply for one or more AstraZeneca commercial products. You will identify, develop and implement process improvements using existing and cutting-edge technologies, and provide expert input through laboratory experimentation and in-silico modelling.

The role involves direct manufacturing support at the AZ API site in Dublin and contributing to CMC sections