Senior MES Sustaining & Improvement Engineer

AstraZeneca plc; Dublin; Hybride; EUR 90 000 - 120 000; Plein temps

Résumé du poste

AstraZeneca plc in Ireland seeks a Senior MES Sustaining Engineer to own and support Manufacturing Execution System operations, ensuring compliant, reliable MES performance for commercial manufacturing. You will drive continuous improvements and lead cross-functional collaboration with QA, Validation, Automation and IT teams.

The role emphasizes cGMP compliance, data integrity, cybersecurity, and lifecycle management for MES platforms such as Syncade or PAS-X.

Qualifications

• Supports MES operations in a cGMP environment.
• Experience with Syncade, PAS-X or equivalent MES platforms.
• Familiarity with regulated GxP environments.
• Proven track record in manufacturing support and continuous improvement.

Responsabilités

• Provide MES operations ownership and support for manufacturing systems.
• Lead investigation and resolution of MES incidents and deviations.
• Ensure system availability, reliability and performance for operations.
• Support change controls, risk assessments and validation activities.
• Collaborate with QA, Validation, Automation and IT stakeholders.
• Mentor junior engineers and share MES best practices.

Connaissances

MES architecture

Automation systems

ISA-88 concepts

Change management

Cybersecurity

GxP compliance

Data-driven problem solving

Formation

Bachelor's degree in engineering, Computer Science, Automation, Biotechnology, Pharmaceutical Sciences, or related discipline

Outils

Syncade

PAS-X

DCS/PLC/SCADA integrations

Description du poste

AstraZeneca plc in Ireland seeks a Senior MES Sustaining Engineer to own and support Manufacturing Execution System operations, ensuring compliant, reliable MES performance for commercial manufacturing. You will drive continuous improvements and lead cross-functional collaboration with QA, Validation, Automation and IT teams.

The role emphasizes cGMP compliance, data integrity, cybersecurity, and lifecycle management for MES platforms such as Syncade or PAS-X.