PhD Organic Chemist — API Process Development & Scale-Up

Cpl Group; Dublin; On-site; EUR 70,000 - 95,000; Full time

Benefits offered by this job

Career development

Annual bonus

Education program

Pension

Private healthcare

Competitive base salary

Job summary

SK pharmteco in Swords, Co Dublin, seeks a PhD Chemist to join the R&D team focused on small molecule APIs. The role involves leading development projects, process scale-up, tech transfer, and collaboration with Operations, Quality, and EHS to ensure robust, in-control processes.

The candidate should hold a PhD in organic chemistry with 2+ years in the pharmaceutical industry, strong problem solving, and data-driven decision making for continuous process verification.

Qualifications

• PhD in organic chemistry is required.
• Strong problem solving and continuous improvement mindset.
• Experience working across functions in a matrix organization.
• Ability to manage projects and troubleshoot processes in pharma.

Responsibilities

• Lead development projects in the laboratory, including route scouting and crystallisation optimisation.
• Provide technical support to API/intermediate manufacture with a focus on optimisation.
• Identify and implement process optimisation across scale-up and manufacturing aspects.
• Utilise PAT tools (e.g., FBRM, Raman, IR) for data-driven development and tech adoption.
• Coordinate tech transfer for new products, including process development, customer engagement, and documentation.
• Support chemistry assessments for new products as required.
• Lead throughput/yield optimisation with Operations engineers.
• Support CVP through data trends, OOT, SAE investigations with RD and QC teams.
• Participate in manufacturing campaign performance and quality/safety investigations.
• Collaborate with RD analytical chemists and Operations engineers on scale-up activities.

Skills

Interpersonal skills

Problem solving

Project management

Cross-functional collaboration

Continuous improvement

Education

PhD in organic chemistry

Tools

PAT

Chromatography

Process safety

Job description

SK pharmteco in Swords, Co Dublin, seeks a PhD Chemist to join the R&D team focused on small molecule APIs. The role involves leading development projects, process scale-up, tech transfer, and collaboration with Operations, Quality, and EHS to ensure robust, in-control processes.

The candidate should hold a PhD in organic chemistry with 2+ years in the pharmaceutical industry, strong problem solving, and data-driven decision making for continuous process verification.