Neurovascular Postdoc: Dual-Cell Therapy Research Lead

Fastnet; Dublin; On-site; EUR 42,000 - 56,000; Full time

Job summary

Fastnet in Dublin is seeking a Postdoctoral Researcher to contribute to development of an innovative dual‑cell therapy for neonatal brain injury, focusing on hypoxia-associated conditions and MoA.

The role involves designing hypoxia models, conducting proteomic and transcriptomic analyses, establishing CQAs, and preparing release assays, with mentoring and collaboration across the consortium.

Qualifications

• PhD in neuroscience or related field with at least 3 years of postdoctoral experience.
• Proven experience in developing and validating in vitro and/or in vivo models of hypoxia or neurovascular injury.
• Strong expertise in cell biology, especially MSCs and ECFCs.
• Experience with proteomics and transcriptomics (RNA-seq) for MoA studies.
• Experience defining CQAs and potency release criteria for ATMPs.
• Hands-on experience with neuronal models and translational research.
• Experience leading or mentoring research staff or students.

Responsibilities

• Design, establish, and optimize in vitro hypoxia models.
• Validate models for reproducibility and translational relevance.
• Conduct omics analyses (proteomics and RNA-seq) to elucidate MoA.
• Define and characterize CQAs for MSCs and ECFCs.
• Develop release assays to ensure product consistency.
• Collaborate with consortium members to integrate assays into GMP.
• Prepare detailed reports and present findings at meetings.

Skills

Neuroscience

Cell therapy

Regenerative medicine

MSCs

ECFCs

Proteomics

Transcriptomics

MoA studies

CQAs

Potency assays

ATMPs

In vivo models

Data analysis

Leadership

Education

PhD in neuroscience or related field

Tools

RNA-Seq

Proteomics workflows

Job description

Fastnet in Dublin is seeking a Postdoctoral Researcher to contribute to development of an innovative dual‑cell therapy for neonatal brain injury, focusing on hypoxia-associated conditions and MoA.

The role involves designing hypoxia models, conducting proteomic and transcriptomic analyses, establishing CQAs, and preparing release assays, with mentoring and collaboration across the consortium.