Senior Scientist, Ion Channel Pharmacology & Ephys

Sygnature Discovery

Glasgow

On-site

GBP 90,000 - 120,000

Full time

5 days ago
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Benefits offered by this job

25 days annual leave
Private Medical Insurance
Life Insurance
Employee Assistance Programme
Enhanced Family Friendly Policies
Sygnature Group Pension Scheme
1 paid volunteer day per year

Job summary

Sygnature Discovery is seeking an experienced Principal Scientist / Associate Principal Scientist with a strong ion channel background to join our established CRO. You will provide scientific leadership across electrophysiology projects, support multiple client programmes, and drive assay development and innovation.

You will mentor scientists and contribute to business development within a growing Electrophysiology and Cellular Pharmacology group.

Qualifications

  • PhD or equivalent in a relevant life sciences discipline.
  • Significant electrophysiology experience (manual or automated patch clamp).
  • Strong expertise in ion channel pharmacology and assay development.
  • Proven ability to lead complex scientific projects and solve technical challenges.
  • Excellent communication, presentation and client-facing skills.
  • Experience mentoring or line managing scientific staff.
  • Experience across GPCRs and transporter biology is advantageous.

Responsibilities

  • Provide scientific leadership across electrophysiology and pharmacology projects, including study design, execution, analysis and interpretation.
  • Act as a subject matter expert in ion channel pharmacology and electrophysiology to support client programmes.
  • Lead assay development, optimisation, validation and troubleshooting activities.
  • Collaborate with multidisciplinary teams to ensure timely, high-quality project delivery.
  • Drive innovation through new technologies and workflows.
  • Build strong client relationships via scientific discussions and data presentations.
  • Support business development and growth of electrophysiology services.
  • Mentor and develop scientists within the team, including line management.

Skills

Ion channel pharmacology
Electrophysiology
Leadership & project oversight
Client-facing communication
Mentoring staff
GPCRs & transporters exposure
Drug discovery experience

Education

PhD in Pharmacology/ Physiology/ Neuroscience/ Cell Biology
BSc/MSc with substantial industrial drug discovery experience

Job description

Sygnature Discovery is seeking an experienced Principal Scientist / Associate Principal Scientist with a strong ion channel background to join our established CRO. You will provide scientific leadership across electrophysiology projects, support multiple client programmes, and drive assay development and innovation.

You will mentor scientists and contribute to business development within a growing Electrophysiology and Cellular Pharmacology group.

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