Ion Channel Pharmacology Lead - Sr Principal Scientist/AD

Sygnature Discovery

Glasgow

On-site

GBP 90,000 - 130,000

Full time

14 days+
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Benefits offered by this job

25 days annual leave
Private medical insurance
Life insurance
Employee assistance programme
Enhanced family policies
Sygnature pension scheme
1 paid volunteer day per year

Job summary

Sygnature Discovery in Glasgow seeks a Senior Principal Scientist / Associate Director to provide scientific, strategic and operational leadership within the Electrophysiology & Cellular Pharmacology group. You will steer a portfolio of electrophysiology programmes, shape study design, and drive high-quality outcomes for biotech and pharmaceutical clients worldwide.

You will set experimental direction, manage cross-functional teams, and expand the electrophysiology service offering while

Qualifications

  • PhD or equivalent industrial experience required in pharmacology/neuroscience.
  • Extensive electrophysiology experience including patch clamp; CRO/biotech exposure.
  • Deep ion channel pharmacology knowledge with drug discovery experience.
  • Proven track record leading complex scientific programmes and delivering outcomes.
  • Strong client-facing skills and ability to build trusted client relationships.
  • Experience contributing to business development, proposals, and study design.
  • Experience mentoring and managing scientific staff; leadership capability.

Responsibilities

  • Oversee execution of client projects with scientific excellence and timely delivery.
  • Lead assay development, optimization, validation, and implementation.
  • Provide scientific oversight across multiple programmes and resolve risks.
  • Build and maintain relationships with biotech and pharma clients as a trusted partner.
  • Contribute to business development through proposals and discussions.
  • Drive growth of electrophysiology and ion channel service offerings.
  • Collaborate with leadership to define strategy and capability development.
  • Lead, mentor, and develop scientists to foster excellence and improvement.

Skills

Ion channel pharmacology
Electrophysiology (patch clamp)
Lead scientific programmes
Client-facing communication
Business development
Mentoring and staff development
Scientific strategy and study design

Education

PhD in Pharmacology/Physiology/Neuroscience/Cell Biology

Job description

Sygnature Discovery in Glasgow seeks a Senior Principal Scientist / Associate Director to provide scientific, strategic and operational leadership within the Electrophysiology & Cellular Pharmacology group. You will steer a portfolio of electrophysiology programmes, shape study design, and drive high-quality outcomes for biotech and pharmaceutical clients worldwide.

You will set experimental direction, manage cross-functional teams, and expand the electrophysiology service offering while

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