Senior Scientist, Immunogenicity & Ligand Binding Assays

BioSpace; Oxford; On-site; GBP 90,000 - 140,000; Full time

Benefits offered by this job

Healthcare benefits

Well-being resources

Family benefits

Paid time off

Savings and investments

Job summary

Moderna is seeking a senior bioanalytical scientist to lead LBA‑based bioanalysis for our mRNA‑LNP programs. You will provide scientific oversight, shape phase‑appropriate strategies, and ensure GLP/GcLP/GCP compliance across the analytical workflow.

You will collaborate with cross‑functional teams to advance immunogenicity and ADA/neutralizing antibody assays through development, validation and regulatory support.

Qualifications

• A Ph.D. in infectious disease, Immuno‑oncology, Immunology, Cancer Biology, or related fields and a minimum of 10+ years of industry biotech/pharmaceutical experience. M.S. with extensive bioanalytical experience are considered
• Experience with RNA, biologics and cell therapy preferred
• Experience of various platforms such as ECL, Gyrolabs, reporter gene assays, DelPhia assays and other methodologies for clinical assays.
• Ability to effectively communicate scientific concepts, program objectives, data analysis within a matrix environment.
• Knowledge of GLP requirements and understanding of current industry trends and regulatory expectations associated with bioanalytical science.
• Experience on Watson LIMS and LabVnatage eLBN would be an advantage.
• A desire to make an impact as part of a high‑growth, transformational companythat is Bold, Relentless, Curious, and Collaborative.

Responsibilities

• Provide scientific oversight of LBA‑based bioanalyses supporting Moderna’s mRNA‑LNP programs.
• Lead Immunogenicity function through phase‑appropriate, risk‑based bioanalytical development strategies.
• Lead and facilitate anti‑drug antibody (ADA) and neutralizing antibody assay development, validation, and clinical testing.
• Ensure in‑house GcLP compliance across the LBA team, systems, and procedures.
• Design and execute phase‑appropriate clinical analytical strategies across development programs.
• Collaborate with multidisciplinary teams to advance analytical approaches and improve processes.

Skills

RNA experience

Biologics

Cell therapy

Regulatory knowledge

Analytical supervision

LBA methodology

Education

Ph.D. in infectious disease, Immuno‑oncology, Immunology, Cancer Biology, or related fields

M.S. with extensive bioanalytical experience

Tools

Watson LIMS

LabVantage eLBN

Job description

Moderna is seeking a senior bioanalytical scientist to lead LBA‑based bioanalysis for our mRNA‑LNP programs. You will provide scientific oversight, shape phase‑appropriate strategies, and ensure GLP/GcLP/GCP compliance across the analytical workflow.

You will collaborate with cross‑functional teams to advance immunogenicity and ADA/neutralizing antibody assays through development, validation and regulatory support.