Senior Scientist, I

AbbVie Inc; Worcester; On-site; GBP 60,000 - 80,000; Full time

Job summary

A leading biopharmaceutical company is seeking a motivated Senior Scientist in Worcester, MA to support pre-clinical bioanalytical studies focused on large molecule therapeutics. The ideal candidate will have a strong background in immunology or biochemistry and experience in assay development, data interpretation, and mentoring. This onsite role offers a comprehensive benefits package and a collaborative environment within the QTAS team.

Benefits

Paid time off

Medical/dental/vision insurance

401(k) plan

Qualifications

• 10+ years of industry experience in bioanalytical studies or related fields.
• Experience conducting DMPK studies and PK/PD/TK bioanalysis.
• Required experience with assay development using ELISA and MSD.

Responsibilities

• Design and execute pre-clinical bioanalytical studies.
• Communicate assay plans and results effectively with teams.
• Mentor and train junior scientists.

Skills

Assay development

Data interpretation

Problem-solving skills

Communication skills

Independent contributor

Education

Bachelor’s degree in biochemistry, chemistry or pharmacology

MS with 8 years of industry experience

PhD with 0+ years experience

Tools

LIMS systems

Ligand binding assay platforms

Data analysis software

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The Quantitative Translational & ADME Sciences (QTAS) team in Worcester, MA, is seeking a motivated and independent Senior Scientist to support pre-clinical bioanalytical studies in a non-regulated environment. This role focuses on understanding large molecule therapeutics, pharmacokinetics, and immunogenicity in safety and efficacy studies.

The primary responsibilities of a Senior Scientist include developing and executing bioanalytical strategies to support PK, PD, and TK studies using ligand binding assay platforms. This lab-based role emphasizes bioanalytical (PK and ADA) assay design, planning, and data interpretation to support oncology, immunology, and neuroscience portfolios.

The ideal candidate will have a strong background in immunology, biochemistry, and/or pharmacology or related fields. The candidate is expected to mentor and train bench scientists and provide scientific reasoning behind bioanalytical assay design and data interpretation.

This position is onsite and located at the AbbVie Bioresearch Center in Worcester, MA.

Duties & Responsibilities

• Design and execute pre-clinical (rodent, NHP) bioanalytical studies using newly developed or existing bioanalytical protocols, using immunoassays, e.g. MSD.
• Effectively and clearly communicate assay plans, timelines, results, and data interpretations with study teams and QTAS stakeholders.
• Serve as a scientific and technical consultant across teams.
• Train and mentor junior scientists.
• Archive data in ELN and LIMS systems.
• Write and update experimental protocols and procedures.
• Initiate, design, interpret, and troubleshoot operational assays independently and efficiently.

Qualifications

• Bachelor’s degree in biochemistry, chemistry, or pharmacology with 10+ years industry experience; MS with 8 years of industry experience, or a PhD with 0+ years experience.
• Previous experience conducting DMPK studies, PK/PD/TK bioanalysis on antibodies, bi/multi-specifics and/or ADCs, including data interpretation is required.
• Highly motivated, reliable, and independent contributor with attention to detail and problem-solving skills.
• Required experience with assay development and troubleshooting using ligand binding workflows (ELISA, MSD) is a must.
• Excellent written and verbal communication skills.
• Proficiency with computers and data analysis software, including LIMS systems.
• Ability to design, summarize, communicate, and interpret bioanalytical results.
• Creative leader and collaborative team player, able to work effectively in a highly matrixed environment.

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html