Senior Scientist, Computational Chemistry

Insmed Incorporated; Cambridgeshire and Peterborough; On-site; GBP 50,000 - 70,000; Full time

Job summary

Insmed, a prominent biopharmaceutical company, seeks a Senior Scientist specializing in Computational Chemistry at its Cambridge facility. This role emphasizes expertise in CADD to optimize drug design for rare diseases, leveraging the latest technologies in a collaborative environment focused on patient-first solutions. Candidates should possess a relevant PhD or MSc, supplemented by significant industry experience and proficiency in computational tools.

Benefits

Flexible work approach

Health benefits and time-off plans

Competitive compensation package

Equity Awards (Long-Term Incentives)

Employee Stock Purchase Plan (ESPP)

Qualifications

• 4-5 years of industry experience in computational chemistry.
• Hands-on experience with protein structure prediction and molecular modeling.
• Proficiency in programming languages like Python or R is a plus.

Responsibilities

• Apply CADD to aid design and optimization of therapeutic molecules.
• Collaborate with interdisciplinary teams to integrate computational findings.
• Contribute towards developing an advanced computational chemistry platform.

Skills

Computer-Aided Drug Design (CADD)

Molecular Docking

Molecular Dynamics

Quantitative Structure-Activity Relationship (QSAR)

Protein Structure Prediction

Data Analysis

Education

PhD or MSc in Computational Chemistry, Structural Biology, or related field

Tools

Schrödinger

MOE

Gaussian

Job description

Senior Scientist, Computational Chemistry

Join to apply for the Senior Scientist, Computational Chemistry role at Insmed Incorporated

Senior Scientist, Computational Chemistry

Join to apply for the Senior Scientist, Computational Chemistry role at Insmed Incorporated

Direct message the job poster from Insmed Incorporated

At Insmed Cambridge, we are seeking a talented Computational Senior Scientist! You will bring your expertise in Computer-Aided Drug Design (CADD) to develop a new design and make platform. We discover novel targets to generate first in class therapeutics that serve patients with rare diseases, join in!

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Responsibilities

• Apply CADD to drive project progression. Using computational chemistry tools and techniques (such as molecular docking, molecular dynamics, QSAR, and free energy calculations) to aid the design and optimization of small molecules, oligonucleotides, and biologics.
• Collaborate with interdisciplinary teams including Medicinal Chemists, Data Scientists, Biologists and external partners to integrate computational findings into drug discovery projects.
• Apply protein structure generation and analysis, homology modelling, and protein-ligand interaction studies to aid designing molecules.
• Contribute towards the design and development of a pioneering computational chemistry platform that integrates artificial intelligence, machine learning, and other advanced technologies for data-driven drug discovery.
• Bring and develop knowledge that allows us to get in front of and invest the latest advancements in CADD, protein structure modelling, and AI applications.
• Analyse and interpret large datasets from molecular modeling, virtual screening, and protein-ligand interaction studies to provide actionable insights for drug development programs.

What we are looking for

• PhD or MSc in Computational Chemistry, Structural Biology, Biochemistry, or a related field with industry experience (4-5 years +).
• Strong expertise in CADD tools - Schrödinger, MOE, Gaussian, or other industry-standard software) for small molecule, oligonucleotide, or biologic design.
• Hands-on experience inprotein structure prediction, homology modelling, and a keen interest in exploring novel methods for protein structure generation.
• Demonstrated ability to work with physics based methods including MD simulation and use of free energy methods.
• Proficiency in programming languages like Python or R and data visualization tools (such as Spotfire) is a plus.

At Insmed, we’re committed to investing in every team member’s total well-being, now and in the future. Our benefit programs vary by country but we offer the following to all Insmed team members, regardless of geographic location:

• Flexible approach to how we work
• Health benefits and time-off plans
• Competitive compensation package, including bonus
• Equity Awards (Long-Term Incentives)
• Employee Stock Purchase Plan (ESPP)

Additional Information

Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at [e-mail] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research

• Industries

  Biotechnology Research and Pharmaceutical Manufacturing

Referrals increase your chances of interviewing at Insmed Incorporated by 2x

Sign in to set job alerts for “Chemist” roles.

Cambridgeshire, England, United Kingdom 3 days ago

Cambridge, England, United Kingdom 4 days ago

Cambridge, England, United Kingdom 2 days ago

Cambridgeshire, England, United Kingdom 3 days ago

Cambridgeshire, England, United Kingdom 1 day ago

Cambridge, England, United Kingdom 1 week ago

Cambridgeshire, England, United Kingdom 3 days ago

Cambridgeshire, England, United Kingdom 5 days ago

Cambridge, England, United Kingdom 4 days ago

Huntingdon, England, United Kingdom 1 day ago

Cambridge, England, United Kingdom 2 weeks ago

Senior Scientist, Computational Chemistry

Babraham, England, United Kingdom 2 days ago

Wisbech, England, United Kingdom 14 hours ago

Cambridge, England, United Kingdom 4 days ago

Cambridge, England, United Kingdom 2 weeks ago

Cambridge, England, United Kingdom 1 day ago

Huntingdon, England, United Kingdom 3 days ago

Cambridge, England, United Kingdom 4 days ago

Clinical Scientist / Senior Clinical Scientist

Cambridge, England, United Kingdom 1 week ago

Cambridgeshire, England, United Kingdom 5 days ago

Huntingdon, England, United Kingdom 2 weeks ago

Cambridge, England, United Kingdom 3 months ago

Cambridge, England, United Kingdom 1 week ago

Cambridge, England, United Kingdom 2 months ago

Cambridge, England, United Kingdom 3 months ago

Cambridge, England, United Kingdom 4 days ago

Cambridge, England, United Kingdom 2 weeks ago

Cambridgeshire, England, United Kingdom 2 weeks ago

Whittlesford, England, United Kingdom 1 day ago

Cambridgeshire, England, United Kingdom 2 weeks ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.