Senior Scientist, Automated Pathogen Diagnostics Platform

1000scholars

Oxford

On-site

GBP 70,000 - 110,000

Full time

2 days ago
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Job summary

EIT - Ellison Institute of Technology in Oxford, United Kingdom seeks a Senior Scientist, Automated Diagnostic Systems to translate molecular biology workflows into automated diagnostic platforms. You will lead automation of nucleic acid extraction, library prep, and sample processing within a fluidic device, guiding from concept to prototype.

Collaborating with engineers, chemists, and other scientists, you’ll apply DoE and quantitative methods to optimize performance, reduce risk, and improve

Qualifications

  • PhD (or equivalent industry experience) in Biotechnology, Molecular Biology, Bioengineering, Biochemistry, or a related discipline.
  • Experience developing molecular biology workflows in industrial or translational R&D environments.
  • Proven track record of automating or semi-automating molecular biology workflows.
  • Experience integrating biological workflows into analytical, diagnostic, or cartridge-based platforms.
  • Strong understanding of nucleic acid extraction, purification, and analysis across diverse sample types.
  • Ability to design robust experiments and interpret results within complex systems.
  • Experience identifying and resolving bottlenecks in integrated biochemical workflows.
  • Strong understanding of assay performance, reproducibility, and quantitative development metrics.
  • Experience balancing biological requirements with engineering constraints such as fluidics, automation, contamination control, and reagent stability.
  • Proven ability to work effectively in multidisciplinary teams spanning biology, chemistry, and engineering.

Responsibilities

  • Design and execute robust experiments to generate high-quality data and inform technical decisions.
  • Translate molecular biology workflows into automated processes for integration within a diagnostic platform.
  • Apply Design of Experiments (DoE) and quantitative methods to optimise workflow performance.
  • Develop performance metrics and analytical frameworks to support iterative platform development.
  • Identify and resolve bottlenecks, variability, and failure modes across integrated workflows.
  • Generate insights that guide system design, including fluidics, reagents, automation, and overall architecture.
  • Improve assay robustness, reproducibility, and scalability.
  • Collaborate closely with biologists, chemists, and engineers to integrate biological workflows into automated systems.
  • Provide technical leadership by defining experimental strategies, prioritising risks, and supporting prototype development.

Skills

Automation of molecular workflows
Design of Experiments (DoE)
Multidisciplinary collaboration
Nucleic acid extraction & analysis
Prototype development leadership

Education

PhD in Biotechnology / Molecular Biology / Bioengineering

Tools

Cartridge-based platforms
Oxford Nanopore sequencing
Automated library preparation

Job description

EIT - Ellison Institute of Technology in Oxford, United Kingdom seeks a Senior Scientist, Automated Diagnostic Systems to translate molecular biology workflows into automated diagnostic platforms. You will lead automation of nucleic acid extraction, library prep, and sample processing within a fluidic device, guiding from concept to prototype.

Collaborating with engineers, chemists, and other scientists, you’ll apply DoE and quantitative methods to optimize performance, reduce risk, and improve

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