Senior Research Associate II — Stem Cell & Gene Therapy

Piper Companies; Cambridge; On-site; GBP 52,000 - 74,000; Full time

Benefits offered by this job

Medical, Dental, Vision

401k

Paid Holidays

PTO (Paid Time Off)

Sick leave as per law

Job summary

Piper Companies in Cambridge, MA is seeking a highly motivated Senior Research Associate II to support the development of innovative cell-based therapies through hands-on stem cell culture, genetic engineering studies, and translational biology programs.

The role requires 3+ years of pluripotent stem cell work, GMP experience, and proficiency with flow cytometry, RT-qPCR, ddPCR, ELISA, and immunostaining; weekend shifts are scheduled.

Qualifications

• 3+ years of hands-on experience with human pluripotent stem cell culture (IPSC), differentiation, and maintenance.
• Experience in regenerative medicine, cell therapy, gene editing, or related therapeutic development fields.
• Must have experience working in a GMP-regulated biotech/biopharmaceutical environment.
• Extensive experience performing techniques such as flow cytometry, RT-qPCR, ddPCR, ELISA, and immunostaining methods.
• Bachelor's or Master's degree in Biology, Cell Biology, Molecular Biology, Biotechnology, Regenerative Medicine, Genetics, or a related scientific discipline.
• Schedule requires weekend work – 40 hours per week (Thurs-Monday Shift or Fri-Tues)

Responsibilities

• Perform routine culture, expansion, maintenance, and differentiation of human stem cells and other mammalian cell lines.
• Support research initiatives involving cellular engineering, gene modification, and evaluation of cellular function in lab and preclinical settings.
• Monitor cell health, growth, sterility, and experimental quality with detailed records.
• Carry out molecular and cellular biology techniques including nucleic acid extraction, cDNA prep, gene expression analysis, and protein assays.
• Conduct experiments using flow cytometry, qPCR, ddPCR, ELISA, immunofluorescence, and related methods.
• Assist in developing, optimizing, and troubleshooting workflows and SOPs.
• Compile, interpret, and present experimental findings using statistical methods.
• Maintain inventory, prepare reagents, monitor supplies, coordinate purchasing of materials and equipment.

Education

Bachelor's or Master's degree in Biology or related field

Tools

Flow Cytometry

RT-qPCR

ddPCR

ELISA

Immunostaining

Western Blot

Job description

Piper Companies in Cambridge, MA is seeking a highly motivated Senior Research Associate II to support the development of innovative cell-based therapies through hands-on stem cell culture, genetic engineering studies, and translational biology programs.

The role requires 3+ years of pluripotent stem cell work, GMP experience, and proficiency with flow cytometry, RT-qPCR, ddPCR, ELISA, and immunostaining; weekend shifts are scheduled.