Senior Clinical Trial Manager, AI-Driven Trials

Isomorphic Labs; Cambridge; Hybrid; GBP 90,000 - 120,000; Full time

Job summary

Isomorphic Labs in Cambridge, United Kingdom, is seeking a Senior Clinical Trial Manager to lead cross-functional teams through the full clinical trial lifecycle, from startup through close-out, in alignment with ICH/GCP and corporate standards.

You will manage study start-up, site/vendor coordination, data management support, and the creation of trial documents, while mentoring colleagues and driving data-informed improvements in a fast-paced, collaborative biotech environment.

Qualifications

• Bachelor's degree in a related field with relevant industry experience.
• 3+ years managing oncology or rare disease trials.
• Thorough understanding of GCP/ICH guidelines and cross-functional clinical processes.
• Excellent interpersonal and communication skills for relationship building.
• Proactive problem solving, planning and project management skills.
• Strong outsourced model experience with vendor budgets.

Responsibilities

• Lead cross-functional teams through all activities in the clinical trial lifecycle per ICH/GCP and corporate standards.
• Explore and leverage emerging AI technologies to streamline contract lifecycle management and improve efficiency.
• Build strong cross-functional relationships and mentor team members to drive solutions.
• Manage Change Orders, re-scoping with vendors, and cost-invoice alignment.
• Assist CRO in eTMF development and maintenance to ensure audit readiness at study close.

Skills

GCP/ICH knowledge

Cross-functional leadership

Vendor management

Budget management

Travel willingness

Education

Bachelor's degree in related field

Job description

Isomorphic Labs in Cambridge, United Kingdom, is seeking a Senior Clinical Trial Manager to lead cross-functional teams through the full clinical trial lifecycle, from startup through close-out, in alignment with ICH/GCP and corporate standards.

You will manage study start-up, site/vendor coordination, data management support, and the creation of trial documents, while mentoring colleagues and driving data-informed improvements in a fast-paced, collaborative biotech environment.