Senior Bioinformatics Engineer – DRAGEN Array

Illumina; Great Abington; On-site; GBP 64,000 - 96,000; Full time

Job summary

Illumina seeks a Bioinformatics Scientist/Engineer for the DRAGEN Array team in the UK. You will develop algorithms and production‑quality software for genotyping and genetics, work with wet-lab scientists, and implement robust computational workflows for array/NGS data.

You will apply ML and statistical methods at scale and help improve CI/CD and observability. You will bring a PhD in a relevant field, strong coding in Python or R, experience with genomic data, and a track record in production

Qualifications

• PhD in Bioinformatics, Computational Biology, Computer Science, Biostatistics, Bioengineering, or a related field
• Strong algorithm development and statistical modelling expertise
• Experience with genomic data analysis at scale
• Programming expertise in Python and/or R
• Experience with production software development practices
• Knowledge of testing automation, CI/CD and software lifecycle processes
• Excellent communication and collaboration skills

Responsibilities

• Lead the design and development of algorithms and probabilistic models for analysis of array and NGS data supporting genotyping and genetics applications
• Apply statistical, computational, and machine‑learning methods to large‑scale genetic and epigenetic datasets
• Design and develop production‑grade software that automates analytical workflows and enables robust analysis at scale
• Contribute to software testing automation, including unit, integration, and regression testing of bioinformatics pipelines
• Define and maintain CI/CD workflows to support continuous integration, validation, and reliable delivery of DRAGEN Array software
• Implement and evolve telemetry, logging, and monitoring to improve observability, diagnostics, and operational robustness
• Execute and improve Software Lifecycle practices, including requirements traceability, design documentation, verification, and validation
• Use tools such as JAMA and JIRA to support structured, high‑quality software development
• Collaborate closely with wet‑lab scientists, product management, and engineering teams to translate scientific needs into validated computational solutions
• For staff level, provide mentorship and technical guidance to other scientists and engineers, and contribute to best practices in algorithm design, software engineering, and data analysis

Skills

Bioinformatics

Algorithm development

Statistical modelling

Python

R

Production software development

CI/CD

Testing automation

Data analysis

Communication

Education

PhD in Bioinformatics/Computational Biology/CS/Biostatistics/Bioengineering

Tools

JAMA

JIRA

Job description

Illumina seeks a Bioinformatics Scientist/Engineer for the DRAGEN Array team in the UK. You will develop algorithms and production‑quality software for genotyping and genetics, work with wet-lab scientists, and implement robust computational workflows for array/NGS data.

You will apply ML and statistical methods at scale and help improve CI/CD and observability. You will bring a PhD in a relevant field, strong coding in Python or R, experience with genomic data, and a track record in production