Scientist II/ Sr Scientist - Protein Mass Spectrometry

Abzena; Cambridge; On-site; GBP 35,000 - 40,000; Full time

Job summary

Abzena in Cambridge (UK) seeks an analytical scientist at Scientist II level to join the busy Analytics group. In this lab-based role you will work with a team on client-facing projects and learn new techniques in a fast-paced, supportive environment.

The Analytics group provides analytical solutions across research areas including antibody/ADC characterisation and quality attributes. State-of-the-art instrumentation is available, with opportunities to contribute to advanced research and client

Qualifications

• Ideal candidate has a PhD or MSc in Analytical Science, Protein Chemistry/ Biochemistry or related field with strong laboratory skills.
• Knowledge and practical experience of chromatographic and electrophoretic techniques for small molecules, biologics and bioconjugates.
• Experience in an industrial or commercial environment preferred; SEC-MALS and mass spectrometry are assets.

Responsibilities

• Design and carry out routine and complex experiments as necessary.
• To perform and develop complex/novel analytical methods under supervision.
• Maintain and troubleshoot instrumentation.
• Manage own work schedule to ensure tasks are met within the expected timeframe.
• Analyse and interpret your own data.
• Be responsible for the quality of your own work.
• Prepare data for, contribute to the drafting of reports and presentations.
• Contribute to internal and client meetings.
• Draft and contribute to Quality and Controlled documents.
• Undertake any other duties relevant to the position and level.

Skills

Analytical skills

Lab techniques

Chromatography

Electrophoresis

Data analysis

Communication skills

Teamwork

Education

PhD or MSc in Analytical Science / Protein Chemistry / Biochemistry or related

Tools

Chromeleon

Unifi/MassLynx

Astra

Mass spectrometry

uHPLC

Job description

We have a vacancy at Scientist II level for an analytical scientist to join our busy Analytics group in Cambridge (UK). In this lab-based role you will be working as part of a team on client-facing projects and will have the opportunity to learn new techniques in a fast-paced and supportive environment.

Abzena provides the most complete set of solutions in integrated early discovery to mid-phase biotherapeutic and ADC drug development services in the pharmaceutical industry. Working with a varied range of customers from academic groups, small biotech and big pharma and on a diverse range of drug types from antibodies, fusion proteins and bioconjugates, Abzena supports the development and manufacture of better treatments for patients.

The Analytics group in Abzena Cambridge (UK) provides analytical solutions and developments concerning all areas of research in Abzena, such as antibody and ADC characterisation, determination of critical quality attributes of biopharmaceuticals, forced degradation stability studies, formulation development, immuno-peptidomics. To support Abzena’s biotherapeutic research activities the Analytics lab in Cambridge is equipped with state-of-the-art instrumentation including triple-quad mass spectrometers and high-resolution Q-TOF, high sensitivity TOF, and Orbitrap mass spectrometers, uHPLC chromatography, capillary electrophoresis, dynamic light scattering platforms.

Ideally, you will have a PhD or an MSc (or a lower level of qualification and relevant experience) in Analytical Science, Protein Chemistry/ Biochemistry or related science discipline with strong laboratory skills and experience in an industrial or commercial environment. You will have a good understanding of analytics and its application in biotherapeutic drug development. Knowledge and practical experience (including experimental planning, sample preparation, instrument set-up, and data analysis) of chromatographic and electrophoretic techniques for small molecule, biologics and bioconjugates are the core requirements for this role. Experience of SEC-MALS analysis and mass spectrometry would be an asset. As a confident IT user, you will be familiar with MS Office, and specialist software including Chromeleon, Unifi/MassLynx, Astra.

You will be able to work both independently and as part of a team, have good planning and organising skills. In addition, you will have a high level of attention to detail and a quality-oriented mindset (experience in a regulated set-up will be considered as an asset). You will be able to identify and analyse and resolve routine and complex problems autonomously and proactively. You will demonstrate ability to communicate clearly both orally and in writing, keeping team and management informed. You will contribute to the group development effort undertaking advanced research, undertaking client projects and interactions in a professional manner.

In return, we can offer you a competitive salary and benefits package and a collaborative, varied and challenging environment where you will be encouraged to step outside your comfort zone and develop your career.

Responsibilities

• To design and carry out routine and complex experiments as necessary

• To perform and develop complex/novel analytical method under supervision

• To maintain and troubleshoot instrumentation

• To manage own work schedule to ensure tasks are met within the expected timeframe

• To analyse and interpret your own data

• To be responsible for the quality of your own work

• To prepare data for, contribute to the drafting of reports and presentations

• To contribute to internal and client meetings

• To draft and contribute to Quality and Controlled documents

• To undertake any other duties relevant to the position and level

£35,000 - £40,000 a year

Abzena is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, colour, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws.

This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, and training.