Scientist Downstream Process Development

Accord Healthcare; Harrow; On-site; GBP 42,000 - 64,000; Full time

Benefits offered by this job

Holiday allowance

Bonus

Pension scheme

Job summary

Accord Healthcare is seeking a Research Scientist to design, optimise and scale downstream purification for biologics at our Harrow site. You will lead purification strategies for monoclonal antibodies and proteins, spanning early to late-stage development, with emphasis on robust, scalable processes and technology transfer.

The role requires practical experience with chromatography systems (ÄKTA), filtration platforms, and DoE tools, plus interpretation of analytical data (HPLC/CE-SDS/SEC).

Qualifications

• Degree educated in a relevant bioprocessing discipline.
• Hands-on experience with chromatography systems (ÄKTA) and filtration platforms.
• Proficiency with DoE tools, Unicorn, and JMP for data analysis.
• Experience in biologics or biosimilar development is advantageous.
• Able to interpret analytical data (HPLC, CE-SDS, SEC).
• Strong knowledge of downstream bioprocessing and protein purification.
• Understanding of CQAs, process optimisation, and scale-up.
• Familiarity with GMP and ICH guidelines.

Responsibilities

• Design, optimise, and scale downstream purification for biologics.
• Support biosimilar development and commercialisation activities.
• Contribute to process characterisation, scale-up, and tech transfer.
• Advance platform process development and continuous purification strategies.
• Ensure processes are robust, compliant with regulatory/quality requirements.

Skills

Chromatography

Filtration

DoE tools

Unicorn

JMP

Biologics knowledge

HPLC

GMP/ICH

Scale-up

Process optimisation

Education

Bioprocessing/Biotechnology degree

Tools

ÄKTA chromatography system

Job description

Research Scientist - Downstream Process Development

Role: Full-time, permanent

Location: Harrow, West London

Salary: Competitive + bonus + benefits

The Role:

The DSP Scientist will design, optimise, and scale, downstream purification processes for therapeutic biologics, including monoclonal antibodies and proteins, supporting biosimilar development and commercialisation. The role spans early- and late-stage process development, including process characterisation, scale-up, and technology transfer.

It also focuses on platform process development, process intensification (including continuous purification), and viral safety strategies, ensuring processes are robust, scalable, and compliant with regulatory and quality requirements.

Additionally, the role supports product lifecycle management activities and contributes to technical discussions with global partners.

The Person:

• Degree educated in relevant discipline
• Hands‑on experience with chromatography systems (e.g., ÄKTA) and filtration platforms.
• Proficiency with DoE tools, Unicorn, and statistical/data analysis software like JMP.
• Experience in biologics or biosimilar development is advantageous.
• Ability to interpret analytical data (e.g., HPLC, CE-SDS, SEC).
• Strong knowledge of downstream bioprocessing and protein purification.
• Understanding of CQAs, process optimisation, and scale‑up.
• Familiarity with GMP and ICH guidelines.

The Rewards:

In return, we offer a competitive salary and rewards package (including holiday, bonus and pension scheme). Not to mention the opportunity to genuinely make a difference in a new and dynamic role within a progressive and expanding business, at an exciting time of growing international reach.