Scientist - Downstream Process Development

Accord Healthcare; Harrow; On-site; GBP 65,000 - 90,000; Full time

Benefits offered by this job

Holiday entitlement

Bonus

Pension scheme

Job summary

Accord Healthcare in Harrow, North West London, is seeking a Research Scientist in Downstream Process Development (DSP) to design, optimise and scale purification steps for biologics including monoclonal antibodies. You will contribute across early- and late-stage development, with emphasis on process characterised, scale-up and tech transfer.

You will apply DoE methods, work with chromatography systems (ÄKTA) and filtration platforms, and analyse data to drive robust, regulatory-compliant

Qualifications

• Hands-on chromatography and purification experience.
• Strong data analysis and DoE proficiency.
• Experience with biologics or biosimilar development is advantageous.

Responsibilities

• Design, optimise and scale downstream purification processes for biologics.
• Support early- and late-stage process development, including process characterisation, scale-up and tech transfer.
• Develop platform processes, process intensification and viral safety strategies to ensure robust, scalable, regulatory-compliant processes.
• Contribute to lifecycle management and engage in technical discussions with global partners.

Skills

Chromatography experience

Data analysis

Adaptable in R&D

Education

Master’s degree in a relevant field

Bachelor’s degree with significant relevant experience

Tools

ÄKTA chromatography system

Unicorn

JMP

Job description

Research Scientist Downstream Process Development (DSP)

Role: Full-time, permanent

Location: Harrow, North West London

Salary: Competitive + bonus + benefits

The Role:

The Research Scientist (DSP) will help to design, optimise, and scale downstream purification processes for therapeutic biologics, including monoclonal antibodies and proteins, supporting biosimilar development and commercialisation. The role spans early- and late-stage process development, including process characterisation, scale-up, and technology transfer.

It also focuses on platform process development, process intensification (including continuous purification), and viral safety strategies, ensuring processes are robust, scalable, and compliant with regulatory and quality requirements.

Additionally, the role supports product lifecycle management activities and contributes to technical discussions with global partners.

The Person:

• Master’s degree or bachelor’s degree with significant relevant experience.
• Hands-on experience with chromatography systems (e.g., ÄKTA) and filtration platforms.
• Proficiency with DoE tools, Unicorn, and statistical/data analysis software like JMP.
• Experience in biologics or biosimilar development is advantageous.
• Ability to interpret analytical data (e.g., HPLC, CE-SDS, SEC).
• Adaptable in a dynamic R&D environment

The Rewards:

In return, we offer a competitive salary and rewards package (including holiday, bonus and pension scheme). Not to mention the opportunity to genuinely make a difference in a new and dynamic role within a progressive and expanding business, at an exciting time of growing international reach.