26N/PPSD - Protein Purification Scientist

Randox Laboratories; Crumlin; On-site; GBP 30,000 - 40,000; Full time

Job summary

Randox Laboratories seeks a highly motivated Protein Purification Scientist to enhance their team in Crumlin, Northern Ireland. This role encompasses the entire spectrum of downstream processing and protein purification, from R&D through to pilot and process scale.

Ideal candidates will have a BSc in Biochemistry or related fields, proficiency in FPLC purification techniques, and the ability to work both independently and collaboratively. The position offers a full-time, permanent contract with generous working hours.

Qualifications

• BSc or higher in a related field.
• Ability to work independently and within a team.
• Knowledge of protein purification techniques.

Responsibilities

• Perform FPLC purification using various chromatography techniques.
• Prepare resins, columns, and buffers for processes.
• Conduct routine maintenance and calibration of equipment.

Skills

FPLC purification

Chromatography methods

Analytical methods

Data analysis

Microsoft Office proficiency

Education

BSc in Biochemistry, Biochemical Engineering or related subject

Tools

HPLC/UPLC

Mass-Spec

Job description

Protein Purification Scientist (Job Ref: 26N/PPSD)

Randox is a world leader in diagnostics for clinical healthcare, toxicology, and food security. Our expertise and product portfolio have assisted laboratories across the world in improving health and saving lives. We are proud to have been named the Number 1 company in Northern Ireland for the second consecutive year in the Belfast Telegraph Top 100 Companies List for 2024.

We require highly motivated Protein Purification Scientists to join our growing downstream processing team for the processing of proteins from recombinant and native sources (animal and human derived materials). Scientists will be involved in all aspects of the development, implementation and operation of downstream processing and protein purification from R&D to pilot and process scale.

Location: 61 Largy Road, Crumlin, Co Antrim, BT29 4RR.

Contract: Full‑time, Permanent.

Working hours: 4 × 10 hour shifts, 7.30 am to 6.10 pm Monday to Thursday or Tuesday to Friday.

Right to work requirement: Candidates must have the legal right to work in the UK for a minimum of 12 months from the application date. The role includes a 9‑month probationary period; visa sponsorship will not be offered at the point of hire.

Key duties of the role include:

• FPLC purification using multiple chromatography types (Affinity, IEX, SEC, etc.)
• Preparation of resins and columns for chromatography
• Preparation of buffers for all processes
• Chemical extraction and precipitation of raw materials
• Centrifugation
• Normal flow/depth filtration
• Tangential flow filtration for concentration and diafiltration
• Analytical methods for in-process and final product QC
• Routine maintenance and calibration of equipment

Essential attributes:

• BSc in Biochemistry, Biochemical Engineering or related subject area.
• Ability to work independently within a multidisciplinary research team.
• Excellent organisational and communication skills (written and oral).
• Knowledge of purification methods.
• Ability to interpret and analyse data.
• Proficiency in Microsoft Office (Word, Excel, PowerPoint, Outlook).

Desirable:

• Postgraduate qualification in a related field.
• Experience with FPLC or other protein purification.
• Experience with analytical methods (e.g., HPLC/UPLC, Capillary Electrophoresis, Mass‑Spec, SDS‑PAGE).
• Understanding of protein chemistry.
• Experience in method development in an industrial setting.