Scientist 1 Antibody Engineering & Biologics Design

Evotec; England; On-site; GBP 65,000 - 95,000; Full time

Benefits offered by this job

Pension on completion probation 5%/5%

25 days holiday

Private health insurance

Wellbeing support

Private dental cover

Bonus scheme

Career progression

Cycle-to-work

Refer a friend

Job summary

Evotec is seeking an experienced Senior Scientist 1 to join the Protein Sciences team at Alderley Park. You will lead biologics discovery and engineering strategies across internal and client projects, designing and developing therapeutic antibodies and complex biologics.

You will optimize expression and purification workflows, drive data-driven decisions, and coordinate cross-functional teams to meet milestones.

Qualifications

• PhD in Molecular Biology, Protein Engineering, Biochemistry, Biotechnology, Immunology, or a related discipline.
• Minimum 5 years of industrial and/or postdoctoral experience in antibody discovery, engineering, or biologics development.
• Extensive hands-on experience designing and developing therapeutic antibodies and complex biologics.
• Strong expertise in recombinant biologics expression and purification technologies.
• Experience leading projects and collaborating within cross-functional teams.
• Excellent communication and presentation skills with stakeholders.

Responsibilities

• Lead design and execution of biologics discovery and engineering across client and internal projects.
• Design, engineer, express, purify, and characterize monoclonal and bispecific antibodies and other biologics.
• Develop and optimize expression systems and purification workflows for high-quality proteins.
• Drive experimental design and data-driven decision making.
• Identify innovative approaches to improve workflows and outcomes.
• Act as biologics scientific lead, coordinating cross-functional activities and milestones.
• Present findings to internal and external stakeholders with clear recommendations.
• Contribute to publications, conferences, and external collaborations.
• Mentor junior scientists and support technical capability development.

Skills

Biologics discovery

Antibody engineering

Project leadership

Data analysis

Cross-functional collaboration

Scientific communication

Mentoring

Experimental design

Education

PhD in Molecular Biology/Biotech

Tools

Protein purification

Expression systems

Chromatography

Mass spectrometry

Job description

We are seeking an experienced and highly motivated Senior Scientist 1 to join our Protein Sciences team and play a key role in the design and development of next-generation biologic therapeutics.,

• Lead the design and execution of biologics discovery and engineering strategies across multiple client and internal projects.
• Design, engineer, express, purify, and characterize complex biologics, including monoclonal antibodies, bispecific antibodies and other therapeutic biologics.
• Develop and optimize expression systems and purification workflows to deliver high-quality proteins suitable for screening, characterization, and downstream development.
• Drive experimental design and scientific decision-making through robust data analysis, interpretation, and communication of results.
• Identify innovative approaches and emerging technologies to improve biologics discovery and development workflows.
• Act as a biologics scientific lead on projects, coordinating activities across disciplines and ensuring delivery of key milestones.
• Present scientific findings to internal stakeholders and external clients, providing clear recommendations and strategic guidance.
• Contribute to scientific excellence through publications, conference presentations, and external collaborations where appropriate.
• Mentor junior scientists and contribute to the development of technical capabilities within the team.
• PhD in Molecular Biology, Protein Engineering, Biochemistry, Biotechnology, Immunology, or a related discipline.
• Minimum 5 years of industrial and/or postdoctoral experience in antibody discovery, antibody engineering, or biologics development.
• Extensive hands-on experience designing and developing therapeutic antibodies and complex biologic formats.
• Strong expertise in recombinant biologics expression and purification technologies.
• Experience developing and optimizing workflows for challenging and novel biologic molecules.
• Demonstrated ability to design experiments, solve complex scientific problems, and make data-driven decisions.
• Experience leading projects and collaborating effectively within cross-functional teams.
• Excellent communication and presentation skills with the ability to engage both scientific and non-scientific stakeholders.

Desirable

• Experience with bispecific, multispecific, TCR, fusion protein, or other advanced biologics formats.
• Knowledge of developability assessment, molecular optimization, and protein characterization techniques.
• Experience using computational biology, structural modelling, molecular design, or AI-enabled protein engineering tools.
• Track record of publications, patents, conference presentations, or successful therapeutic candidate advancement.
• Previous experience working in a CRO/CDMO or client-facing environment.
• Influence the design of next-generation therapeutic antibodies and protein therapeutics.
• Collaborate with leading biotechnology and pharmaceutical partners.
• Take ownership of high-impact scientific programs from concept through candidate generation.
• Access opportunities for scientific leadership, publication, mentoring, and career development.
• Be part of a collaborative, innovative culture focused on advancing breakthrough medicines for patients worldwide.

Benefits Package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days
• Private health insurance with BUPA for the employee and their partner/family under the company scheme
• Well being support 24/7 and counselling services
• Permanent health insurance provides 75% of the base salary after the qualifying period
• Private dental cover, on completion (but not subject to) of your 3-month probationary period
• Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities
• Cycle-to-work scheme
• Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities at Alderley Park

• The company pays for secure onsite parking
• Restaurant, Café, and Gastro pub
• Gym and workout studio, running, walking, and cycling routes
• Good public transport links with the shuttle bus service.

FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap. EN: In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.