Scientist

Proclinical; Liverpool; On-site; GBP 35,000 - 55,000; Full time

Job summary

Proclinical seeks a dedicated Scientist to develop and optimize downstream processes for biopharmaceutical and vaccine products, bridging laboratory scale with pilot plant operations to support clinical programs.

You will perform downstream purification experiments, apply DoE and statistical analyses, and ensure compliant documentation while collaborating with senior scientists to meet project milestones.

Qualifications

• Degree in Biology, Biochemistry, or a related life sciences discipline.
• Hands-on downstream purification experience in biopharma.
• Experience with chromatography, TFF, and depth filtration.
• Familiarity with scale-up and JMP software.
• GxP knowledge and regulatory compliance.
• Strong technical reporting and communication.
• Team-oriented with collaborative mindset.

Responsibilities

• Plan and run lab and pilot-scale studies on downstream purification.
• Apply DoE and statistics to analyze data and guide projects.
• Write technical reports and transfer process knowledge.
• Maintain GxP compliance and safety documentation.
• Coordinate with team to meet timelines and standards.

Skills

Downstream purification

Design of Experiments

Data analysis

Technical reporting

Collaboration

GxP compliance

Communication

Laboratory teamwork

Scale-up experience

Troubleshooting

Education

Bachelor's degree in Biology, Biochemistry or related life sciences

Tools

FPLC/AKTA systems

Tangential flow filtration (TFF)

Depth filtration

JMP statistical software

Job description

Looking for an opportunity to bridge laboratory innovation with pilot-scale manufacturing and make a real impact on clinical programs?

Proclinical is seeking a dedicated Scientist to focus on the development and optimization of downstream processes for biopharmaceutical and vaccine products. You will play a key role in bridging laboratory-scale experimentation with pilot plant operations, contributing to clinical programs and business milestones. This is an excellent opportunity for individuals with hands‑on experience in downstream purification who are eager to take technical ownership of processes while collaborating with senior scientists.

Responsibilities:

• Plan and execute laboratory and pilot-scale studies, focusing on downstream purification processes such as chromatography, filtration, and centrifugation.
• Utilize statistical tools (e.g., Design of Experiments) to design, analyze, and interpret complex data sets, making informed decisions to guide project direction.
• Author high-quality technical reports and documentation to ensure process knowledge is captured and transferable.
• Maintain compliance with GxP standards during experimental execution and documentation, adhering to safety protocols and established systems of work.
• Support laboratory housekeeping and monitor equipment readiness, including maintenance schedules and liaising with service providers.
• Provide regular updates on project progress to stakeholders and contribute to knowledge-sharing initiatives within the team.
• Collaborate with team members to meet project timelines and technical standards.

Key Skills and Requirements:

• Degree in Biology, Biochemistry, or a related life sciences discipline.
• Hands-on experience in downstream process development or manufacturing within the biopharmaceutical industry.
• Proficiency in downstream techniques such as chromatography (e.g., FPLC, AKTA systems), tangential flow filtration (TFF), and depth filtration.
• Familiarity with process scale-up and statistical analysis tools (e.g., JMP software).
• Understanding of GxP standards and compliance requirements.
• Strong technical reporting and communication skills.
• Ability to work collaboratively in a team-oriented environment.