Research Associate — LNP Formulation & RNA Delivery

gt-bio; Cambridge; On-site; GBP 23,000 - 42,000; Full time

Benefits offered by this job

Health benefits

Hands-on training

Scientific ownership

Job summary

GT Biosciences is seeking a Research Associate to join the Platform Development Team to support lipid nanoparticle formulation and RNA delivery. This hands-on role offers growth in a fast-moving startup environment and a commitment to teaching new wet-lab methods from day one.

The position is in Cambridge, MA, in-person, with an interview process including two virtual interviews and a paid 30-day trial if selected. You will work alongside world‑leading RNA delivery experts.

Qualifications

• B.S. or M.S. in Chemistry, Biochemistry, Bioengineering, Biology, Pharmaceutical Sciences, or a related field.
• At least 1+ years of meaningful hands-on experience in a wet laboratory setting (academic or industry).
• Proficiency with basic laboratory techniques (buffer preparation, serial dilution, pipetting, nucleic acid handling).
• A fast learner who is excited to develop unfamiliar wet-lab skills and become progressively more independent.

Responsibilities

• Prepare lipid nanoparticles and related non-viral delivery systems for mRNA and siRNA.
• Support formulation screens by varying lipid composition and process parameters.
• Perform formulation characterization and quality control measurements (particle size, PDI, encapsulation, RNA concentration, pH).
• Prepare formulations for in vitro and in vivo studies, including dose calculations and sample tracking.
• Maintain basic cell culture responsibilities and support transfection, expression, and knockdown assays.
• Handle precision liquid-handling tasks (multichannel pipetting, serial dilutions).
• Keep meticulous lab records, troubleshoot experiments, and repeat work when needed.

Skills

Wet lab

Pipetting

Record keeping

Nucleic acids

Data analysis

Education

B.S./M.S. in Chemistry/Biochemistry/Bioengineering/Biology/Pharmaceutical Sciences

Tools

DLS

Plate readers

HPLC/UPLC

LC-MS

UV spectroscopy

pH meters

Job description

GT Biosciences is seeking a Research Associate to join the Platform Development Team to support lipid nanoparticle formulation and RNA delivery. This hands-on role offers growth in a fast-moving startup environment and a commitment to teaching new wet-lab methods from day one.

The position is in Cambridge, MA, in-person, with an interview process including two virtual interviews and a paid 30-day trial if selected. You will work alongside world‑leading RNA delivery experts.