Remote Senior Clinical Data Manager - Lead & Own Projects

Warman O'Brien; Milton Keynes; Remote; GBP 65,000 - 90,000; Full time

Job summary

Leading Global CRO is seeking a Senior Clinical Data Manager to own data management deliverables on UK-based remote projects. You will lead study builds, drive data quality, and coordinate with QA during audits.

The role emphasizes team leadership, training, regulatory knowledge (ICH-GCP), and effective client communication. You will develop and maintain key documents such as the DMP and DQRP, manage timelines, and ensure data integrity for regulatory submissions.

Qualifications

• Bachelor’s or Master’s degree in health/pharmaceutical sciences, physical/biological sciences, or chemistry fields.
• 5+ years in pharmaceutical clinical trial data management (or 2+ years as CDM II).
• Strong knowledge of ICH-GCP, data standards, and dataflows.
• Proven leadership in CDM activities and complex projects.

Responsibilities

• Study Build & Design: Lead eCRF design, annotated CRFs, and participate in UAT.
• Data Strategy Documentation: Develop and maintain DMP, Data Management Project Plan, and DQRP.
• Data Cleaning & Harmonisation: Oversee data review, query resolution, SAE reconciliation, and third-party data streams.
• Lock & Archive: Manage post-go-live modifications, locks, and QA coordination.

Skills

CDM leadership

Project ownership

Client relationship management

Regulatory knowledge (ICH-GCP)

Data management processes

Training & mentoring

Education

Bachelor’s or Master’s degree in health/pharmaceutical sciences or chemistry

Tools

EDC systems

Data management tools

Job description

Leading Global CRO is seeking a Senior Clinical Data Manager to own data management deliverables on UK-based remote projects. You will lead study builds, drive data quality, and coordinate with QA during audits.

The role emphasizes team leadership, training, regulatory knowledge (ICH-GCP), and effective client communication. You will develop and maintain key documents such as the DMP and DQRP, manage timelines, and ensure data integrity for regulatory submissions.