Purification Development Scientist (FTC)

AstraZeneca; Cambridge; On-site; GBP 35,000 - 55,000; Full time

Job summary

AstraZeneca is seeking a Purification Development Scientist for a 15-month FTC in Cambridge. You will contribute to the development of purification activities for recombinant proteins, requiring a strong background in biochemistry and bioprocessing. The role involves executing experiments and analyzing biomolecules while collaborating in a dynamic environment focused on innovation and scientific excellence.

Benefits

Competitive Salary

Excellent Employee Benefits

Career development opportunities

Qualifications

• BSc in a related field; postgraduate qualifications preferred.
• Experience with chromatography techniques and biologics downstream process development.
• Familiarity with various biomolecule analysis methods.

Responsibilities

• Design and execute biomolecule purification experiments.
• Analyze biomolecules using HPLC and other standard methods.
• Maintain laboratory records and ensure compliance with safety standards.

Skills

Autonomy

Organizational skills

Teamwork

Adaptability

Analytical skills

Education

BSc in Biochemistry, Bioprocessing, or Biochemical Engineering

Tools

Chromatography systems (AKTA)

Statistical Design software

LIMS

Job description

Job Title: Purification Development Scientist (FTC)

Locations: Cambridge, UK

Salary: Competitive+ Excellent Employee Benefits!

Introduction to role:
Are you ready to explore the depths of science and innovation? As a Purification Development Scientist (15 month FTC), you'll be part of the Purification Process Sciences (PPS) group, driving the development and execution of purification activities. Your work will support our growing portfolio of recombinant proteins and new molecular formats. Dive into the world of biomolecule purification and make a tangible impact!

Accountabilities:
• Design, plan, execute, and report biomolecule purification experiments at various scales, including antibodies, Fc fusion molecules, bispecifics, and more.
• Analyze biomolecules using standard methods such as HPLC, Agarose Gel Electrophoresis, Capillary Electrophoresis, and Spectrophotometry.
• Maintain accurate laboratory records through electronic lab notebooks and data management systems.
• Author reports and internal documentation.
• Conduct general laboratory activities, including buffer preparation and routine equipment maintenance.

Essential Skills/Experience:
• At least a BSc in a related biochemistry/bioprocessing/biochemical engineering field, ideally with further postgraduate qualification and/or extensive postgraduate experience in a related field. Understand the principle of biomolecule manufacturing.
• Experience with chromatography systems (AKTAs) at various scales and a good understanding of chromatography techniques, e.g., Affinity/IEX/HIC. Experience with tangential flow filtration.
• Experience with biologics downstream process development.
• Experience with biomolecule analysis - using standard methods including HPLC, Agarose Gel Electrophoresis, Capillary Electrophoresis, Spectrophotometer.
• Familiar with data management system such as LIMS.
• Demonstrate significant autonomy in terms of experimental design and execution.
• Able to work with multiple projects and serotypes concurrently.
• Hardworking, organized, balanced, and meticulous with an ability to work well under pressure.
• Adaptable and a team player with a conscientious attitude and enthusiasm.
• Participate in group discussions and provide novel solutions to a variety of problems of diverse scope involving basic scientific principles.
• Desire to learn and build on the role.

Desirable Skills/Experience:
• Application of Multifactorial Statistical Design software to the development of Bioprocesses.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca, curiosity meets courage in an inclusive environment where the brightest minds come together. Here, every voice is heard, and all doors are open. We are committed to making a difference by fusing data and technology with scientific innovation to tackle some of the world's most complex diseases. Our passion for science drives us to explore new horizons and make bold decisions that can transform healthcare globally.

Why AstraZeneca?

At AstraZeneca, we stand at the forefront of scientific innovation, passionately merging cutting-edge technology with groundbreaking research to redefine the boundaries of drug discovery and personalized healthcare. We cultivate an environment where curiosity and courage propel us to tackle the biology of complex diseases without fear of failure, driving bold decisions and ambitious breakthroughs.

Our team thrives in a supportive atmosphere, equipped with state-of-the-art resources that empower professionals to celebrate both their triumphs and setbacks. With us, you will not only impact the future of medicine but also enjoy competitive compensation, benefits, and robust career development opportunities. Join us on this exciting journey to make a meaningful impact in the world.

Ready to make an impact? Apply now and be part of our journey to redefine what's possible in science!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

02-Jun-2025

Closing Date

19-Jun-2025 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.