Principal Scientist - Biomarker & Translational Science - Flow Cytometry

VRS Recruitment; Slough; On-site; GBP 65,000 - 90,000; Full time

Job summary

We are seeking a Senior or Principal Research Scientist with strong Flow Cytometry expertise to join a newly forming Translational Research team in Slough. You will support early clinical development, biomarker sciences and gene therapy programmes within a global pharmaceutical context.

The role offers exposure across drug discovery and development, with opportunities to mentor junior scientists and influence project decisions in a collaborative environment.

Qualifications

• Strong hands-on Flow Cytometry assay development and validation experience.
• Immunology background with preclinical to clinical support.
• Proficiency with Flow Cytometry software (FlowJo, BD Diva, FCS Express).
• Ability to work independently in a fast-paced lab and mentor junior scientists.

Responsibilities

• Develop and deliver fit-for-purpose Flow Cytometry assays for pre-clinical and clinical studies.
• Plan, design, execute and interpret experiments to deliver robust data.
• Serve as Flow Cytometry SME, coordinating with internal teams and CROs.
• Understand biology and present data in multi-disciplinary meetings.
• Manage workload to meet project timelines and compliance with safety HTA.

Skills

Flow Cytometry

Immunology

FlowJo

BD Diva

FCS Express

Independent work

Communication

Mentoring

Omics

IHC

Tools

FlowJo

BD Diva

FCS Express

Job description

We are working in partnership with a global pharmaceutical organisation to recruit a Senior or Principal Research Scientist with strong Flow Cytometry expertise for a newly forming Translational Research team.

This opportunity sits within the company’s Early Clinical Development & Translational Sciences function, working closely with an established Biomarker Assay Sciences group. The team supports the progression of innovative therapeutic assets – including gene therapies – from research through to early clinical development.

This is an exciting opportunity for an experienced scientist to play a key role in shaping a new translational capability, while gaining broad exposure across the drug discovery and development pipeline in a highly collaborative environment.

Responsibilities:

• Develop and deliver fit-for-purpose Flow Cytometry assays to support pre-clinical and clinical studies
• Plan, design, execute and interpret experiments, delivering high-quality, robust data
• Act as a Flow Cytometry subject matter expert, working with internal stakeholders and external CROs to share results and drive project completion
• Develop an understanding of the underlying biology and communicate this during multi-disciplinary project meetings
• Present and discuss data within multi-disciplinary project teams
• Manage workload to meet project and portfolio timelines
• Ensure compliance with Health & Safety regulations and HTA requirements

Candidate profile:

• Strong hands-on expertise in Flow Cytometry assay development, validation and data analysis
• Background in immunology and experience supporting pre-clinical to clinical programmes is highly desirable
• Confident using Flow Cytometry software such as FlowJo, BD Diva, FCS Express
• Well organised, detail-focused and comfortable working independently in a fast-paced lab environment
• Confident in communicating complex scientific ideas and data to others
• Broader bioanalytical techniques (e.g. LBA, LC-MS, IHC, omics, exosomes)
• Experience mentoring or managing junior scientists
• Oversight of wider bioanalytical activities within project teams

The role is offered on an initial 12-month contract with realistic potential for extension and permanent opportunities.

Keywords: Flow cytometry, FACS, biomarker, translational science, PK/PD, PK, PD, pharmacodynamic, pharmacokinetic, pharmaceutical, biopharmaceutical, gene therapy, immunology, research, method development, assay development, senior, principal, scientist, Slough, London, Reading, Oxford, Berkshire, Surrey, VRS9538SE