Postdoctoral Scientist

University-of-Oxford; Oxford; On-site; GBP 39,000 - 46,000; Part time

Job summary

University of Oxford is seeking a Postdoctoral Researcher in the Growth Factor Signalling and Ubiquitination group to study proteins linked to childhood brain tumours such as medulloblastoma and glioma at the NDM Research Building, Oxford.

You will develop and perform cellular assays, analyse data, prepare publications, and collaborate while managing your own research and admin. The role is part-time on a fixed-term contract until 31 March 2027, funded by the Department and Cancer Research UK.

Qualifications

• PhD/DPhil in Molecular Biology or closely related field.
• Proven experience with cellular assays for protein degradation & kinase signalling.

Responsibilities

• Develop and perform cellular assays to characterise disease-associated mutants & modulators.
• Analyse and interpret experimental data; prepare publications & presentations.
• Collaborate with researchers and supervise research assistants and PhD students.

Skills

Cellular assays

Data analysis

Scientific writing

Presentation

Collaboration

Project management

Education

PhD/DPhil in Molecular Biology

Tools

GraphPad

Electronic Lab Notebooks

Job description

Centre for Medicines Discovery, NDM Research Building, Old Road Campus, Headington, Oxford, OX3 7FZ

We are seeking a Postdoctoral Researcher to join Professor Alex Bullock’s Growth Factor Signalling and Ubiquitination research group. You will investigate proteins genetically linked to childhood brain tumours, including medulloblastoma and glioma, contributing to research aimed at improving our understanding of the molecular mechanisms underlying these cancers.

You will develop and perform cellular assays to characterise disease-associated genetic mutants and small molecule modulators, with a particular focus on protein degradation and kinase signalling. You will analyse and interpret experimental data, contribute new research ideas, prepare publications and presentations, collaborate with other researchers, and provide guidance to research assistants and PhD students.

You will be responsible for managing your own academic research and administrative duties involving small scale project management, to co-ordinate multiple aspects of work to meet deadlines, as well as maintaining accurate records in an electronic lab notebook. You will be adapting, developing and performing cell assay protocols in protein degradation and kinase signalling to characterise genetic mutants linked to childhood brain tumours.

It is essential that you hold a relevant PhD/DPhil in Molecular Biology or closely related subject. You must have proven technical experience in cellular assays for protein degradation and kinase signalling, including work with cancer mutants and small molecule chemical probes. A good scientific publication record is a must. It is essential that you have competent computer skills including knowledge of graphpad and electronic lab notebooks. It is also essential that you have excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings.

This position is offered part time on a fixed term contract until 31 March 2027 and is funded by both the Department and Cancer Research UK.

Only applications received before 12 midday on Monday, 2 November 2026 will be considered.

Salary (£) : Research Grade 7: Salary in range £39,424 - £46,476 per annum (pro rata). This is inclusive of a pensionable Oxford University Weighting of £1,730 per year (pro rata).