Postdoctoral Researcher – RNA Regulation & ER mRNA

University of Nottingham; Nottingham; On-site; GBP 32,000 - 47,000; Full time

Benefits offered by this job

30 days holiday

Flexible working arrangements

University closure days

Job summary

The University of Nottingham's Catherine Jopling group invites applications for a fixed-term postdoctoral position funded by a BBSRC grant. You will collaborate with the Bushell lab on CCR4-NOT and TENT4/5 proteins in mRNA targeting to the endoplasmic reticulum.

You will design and deliver experiments using CRISPR/Cas9, targeted protein degradation, reporter assays, and RNAseq approaches including SLAMseq and nanopore sequencing, contributing to understanding gene regulation with implications

Qualifications

• Strong interest in RNA regulation mechanisms.
• Expertise in molecular biology and cell culture.
• Experience with CRISPR/Cas9 genome modification.
• Advanced RNA technologies and bioinformatic RNAseq analysis advantageous.
• Excellent analytical skills and ability to communicate and work in a team.

Responsibilities

• Design and deliver experiments to address RNA regulation questions.
• Perform CRISPR/Cas9 genome modification experiments.
• Conduct RNAseq and nanopore-based analyses.
• Collaborate with lab members and discuss findings with the Bushell group.

Job description

The University of Nottingham's Catherine Jopling group invites applications for a fixed-term postdoctoral position funded by a BBSRC grant. You will collaborate with the Bushell lab on CCR4-NOT and TENT4/5 proteins in mRNA targeting to the endoplasmic reticulum.

You will design and deliver experiments using CRISPR/Cas9, targeted protein degradation, reporter assays, and RNAseq approaches including SLAMseq and nanopore sequencing, contributing to understanding gene regulation with implications