Postdoctoral Scientist - Cryo-EM & Transcription-Splicing

UKRI International; Cambridge; Remote; GBP 38,000 - 47,000; Full time

Job summary

UKRI International's MRC Laboratory of Molecular Biology in Cambridge invites applications for a three-year Postdoctoral Scientist position focused on transcription-coupled splicing. The project seeks to understand co-transcriptional spliceosome assembly using a combination of biochemical and structural approaches, including cryo-EM and in vitro reconstitution.

You will join a vibrant, collaborative team and contribute to seminars, publications, and public engagement.

Qualifications

• PhD in a relevant subject or due to complete PhD within 6 months.
• Essential: strong background in structural biology or biochemistry.
• Desirable: experience in cryo-EM, protein purification and biochemical assays.
• Track record of research and publications.

Responsibilities

• Within the programme direction, shape the project goals over a three-year lifespan.
• Plan your work and objectives on a 12-month basis with your Supervisor.
• Work with limited supervision to develop and apply techniques for project goals.
• Introduce and apply new techniques across disciplines as needed.
• Ensure research complies with good practice and policies.
• Contribute to group operations and training of others.
• Engage in a tailored development programme to enhance research skills.

Skills

Structural biology

Biochemistry

Cryo-EM

Protein purification

Biochemical assays

Education

PhD in relevant subject

Job description

UKRI International's MRC Laboratory of Molecular Biology in Cambridge invites applications for a three-year Postdoctoral Scientist position focused on transcription-coupled splicing. The project seeks to understand co-transcriptional spliceosome assembly using a combination of biochemical and structural approaches, including cryo-EM and in vitro reconstitution.

You will join a vibrant, collaborative team and contribute to seminars, publications, and public engagement.