Postdoctoral Researcher - Genome Integrity - UOD2379

1000scholars; Dundee; On-site; GBP 38,000 - 46,000; Full time

Job summary

The University of Dundee invites applications for a Postdoctoral Researcher to join the lab of Professor Adrian Saurin in the Department of Genome Integrity. This fixed-term appointment is for 36 months on a BBSRC-funded project aiming to develop a chemical-genetic system to inhibit cyclin-substrate interactions.

Candidates should have a PhD, at least one first-author publication, and a strong background in cell biology and the cell cycle.

Qualifications

• PhD in a relevant scientific area with at least one first author publication.
• Strong background in cell biology and knowledge of cell-cycle processes.
• Motivated, honest, hard-working and collaborative with excellent organizational skills.

Responsibilities

• Generate and validate new chemical-genetic approaches to inhibit cyclin-substrate interactions.
• Apply phosphoproteomics to identify binding partners and substrates of cyclin/CDKs.
• Use live-cell microscopy and other cell biology methods to study phenotypes from cyclin-substrate inhibition.
• Link observed phenotypes to specific cyclin-substrate interactions.

Skills

Cell biology background

Live-cell microscopy experience

Collaborative and organized

Education

PhD in a relevant scientific area

Job description

We are recruiting a Postdoctoral Researcher to join the of Professor Adrian Saurin in the Department of Genome Integrity at The University of Dundee.

This is a fixed-term appointment for 36 months.

We are looking for a talented researcher to join the lab of Professor Adrian Saurin at the University of Dundee. This is to join a BBSRC-funded project to develop a chemical-genetic system to inhibit cyclin-substrate interactions, based on our recent work developing a similar system to inhibit the PP2A-B56 phosphatase (1) 1) Allan et al, Nature Communications, 2025

Your priorities will include:

• Generating and validating new chemical-genetic approaches to inhibit different cyclin-substrate interactions
• Using cutting-edge (phospho)-proteomics methods to identify binding partners and substrates of specific cyclin/CDKs complexes
• Using a wide range of cell biology methods, including live-cell microscopy, to study the phenotypes associate with inhibition of specific cyclin/CDK subcomplexes
• Linking the observed phenotypes to specific cyclin-substrates interactions

Who we are looking for:

• A highly-motivated and ambitious postdoctoral researcher with a passion for science.
• A candidate with a PhD in relevant scientific area, with at least one first author publication.
• A strong scientific background in cell biology with experience of working on the cell cycle
• Candidates who are motivated, honest, hard-working, collaborative and possess excellent organisational skills

The University of Dundee is rated 1st in Scotland and 2nd in the UK for Medicine (The Times & Sunday Times Good University Guide 2026) and the top university in the UK for Biological Sciences (Research Excellence Framework 2021). The calibre of research at Dundee is high, with 95 per cent of staff working in areas of national or international excellence.

The University of Dundee is a signatory of the Researcher Development Concordat and is committed to enhancing the research environment and culture. Engagement and support of activities which assist the researcher development agenda at the University is therefore essential.

The diversity of our staff and students helps to make the University of Dundee a UK university of choice for undergraduate, postgraduate and distance learning. Family friendly policies, staff networks for BME, Disabled and LGBT staff, membership of Athena SWAN, the ECU Race Equality Charter and Stonewall as well a full range of disability services, create an enjoyable and inclusive place to work.

£37,694 to £46,049 per annum