Postdoctoral Research Associate (Bioinformatician)

University of Oxford; Oxford; On-site; GBP 38,000 - 47,000; Full time

Job summary

An established industry player in biological research seeks a dedicated Post Doctoral Research Assistant to join their innovative team. This role involves leading bioinformatic analyses of complex datasets to uncover the molecular basis of sexual dimorphism in schistosomes. Candidates should have a strong background in bioinformatics and data analysis, with a passion for advancing our understanding of parasitic biology. With a commitment to diversity and equality, this full-time position offers a unique opportunity to contribute to groundbreaking research that impacts global health. If you are eager to make a difference in the field, this role is perfect for you.

Qualifications

• Strong experience in bioinformatic analyses is essential.
• Experience with large-scale sequencing datasets is preferred.

Responsibilities

• Lead the analyses of bulk and single cell ‘omic’ datasets.
• Focus on the transition in schistosomes from cercaria to schistosomula.

Skills

Bioinformatics

Data Analysis

RNA Interference

Genomic Sequencing

Education

PhD in Biology or related field

Tools

Computational Analysis Software

Job description

Location: Life and Mind Building, South Parks Road, OX1 3PS and other departmental buildings in the Radcliffe Observatory Quarter, Oxford

Salary: Researcher Grade 7.1 – 7.8: £38,674 - £46,913 per annum inclusive of an Oxford University weighting

The Parasite Biology Lab, led by Dr Gabriel Rinaldi at the Department of Biology is interested in the fundamental biology of parasitic worms that affect over 1 billion people worldwide. Both experimental and computational approaches are employed to shine light into key biological processes during the life of parasitic flatworms. Large-scale sequencing datasets (‘omics’) are generated and analyzed to reveal cells, genes, proteins and pathways underlying the infection process, parasite development and interaction with the hosts. These findings are further validated byin situlocalization of gene products (e.g. transcripts and proteins) and imaging analysis. The roles of relevant parasite genes and pathways are investigated using gene expression perturbation approaches, such as RNA interference and phenotyping. We are seeking for an enthusiastic Post Doctoral Research Assistant (PDRA) with strong experience in bioinformatic analyses to join our team and lead the analyses of bulk and single cell ‘omic’, multidimensional datasets. These data are part of a research project aiming to decipher the molecular basis of the sexual dimorphism establishment in schistosomes. In particular, the PDRA will focus on the transition between the free-living mammalian infective larva stage (cercaria) ofSchistosoma mansoniand the first intra-mammalian developmental stage (the schistosomula), in both male and females.

The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.

This post is full time and available immediately.

The closing date for applications is 12.00 noon on Wednesday 28th May 2025, interviews are likely to be scheduled for mid June 2025. Applications for this vacancy are to be made onlinethrough our e-recruitment system (via the ‘Apply’ button above), and you will be required to upload a supporting statement and CV as part of your online application.

£38,674 to £46,913 per annum. Grade 7.1 – 7.8