Postdoc: Spatial Lineage Tracing & Single-Cell Multiomics

1000scholars; Greater London; On-site; GBP 38,000 - 47,000; Full time

Benefits offered by this job

Defined benefit pension scheme

Excellent holiday entitlement

Family friendly policies

Discounts on shopping/travel

Employee Assistance Programme

Health and Wellbeing Support

Cycle to work scheme

Settlement and Training Allowances

Job summary

The MRC Laboratory of Medical Sciences in London invites applicants for a fixed-term role focused on spatial single-cell genomics. You will lead the development of DNA methylation barcodes to map cell lineage in intact tissue and adapt capsule chemistry for high-resolution multiomic sequencing with spatial coordinates.

You should hold a PhD (or equivalent) in genomics or a related field and be prepared to work at the bench from day one, analysing your own sequencing data and collaborating across

Qualifications

• PhD or equivalent experience in genomics or related field.
• Ability to bench-scale experiments and analyze sequencing data.
• Aptitude for both experimental and computational work.

Responsibilities

• Lead work on resolving cell lineage in situ and reconstruct lineages.
• Develop DNA methylation barcodes for lineage reconstruction in tissues.
• Adapt semi-permeable capsule chemistry for single-cell multiomic sequencing with spatial coords.

Skills

Genomics

Molecular biology

Computational biology

Education

PhD or equivalent experience

Tools

DNA methylation analysis

Job description

The MRC Laboratory of Medical Sciences in London invites applicants for a fixed-term role focused on spatial single-cell genomics. You will lead the development of DNA methylation barcodes to map cell lineage in intact tissue and adapt capsule chemistry for high-resolution multiomic sequencing with spatial coordinates.

You should hold a PhD (or equivalent) in genomics or a related field and be prepared to work at the bench from day one, analysing your own sequencing data and collaborating across