Postdoc: Antibody Immunotherapy & ADC Discovery

King's College London; City of Westminster; Sur place; GBP 34 000 - 42 000; Plein temps

Résumé du poste

King's College London invites applicants for a Postdoctoral Research Associate in the antibody discovery and immunotherapy program. The appointee will work on cancer immunology, antibody engineering, and ADC generation with translational aims toward first-in-man studies at Guy's Hospital.

You will perform functional assays, flow cytometry, NK cell interactions, and ex vivo organoid models, collaborating across teams led by Prof.

Qualifications

• PhD in Biological Sciences, Cancer Immunology, or related (or near completion).
• BSc in Molecular Biology, Immunology, Biophysics, Biochemistry or related.
• Experience in antibody and antibody-drug conjugate research and generation.
• Experience in antibody functional evaluations (e.g., in vitro, ex vivo cell culture/co-culture, cell-based flow cytometric and ELISA-style assays).

Responsabilités

• Dissect cross-talk between human immunity and breast cancer and test antibodies as diagnostics or therapeutics.
• Engineer Fc-engineered antibodies and antibody-drug conjugates for cancer therapy.
• Translate antibody candidates to first-in-man clinical studies with clinical colleagues at Guy's Hospital.

Connaissances

Cancer immunology

Antibody generation

Antibody functional assays

Team collaboration

Formation

PhD in Biological Sciences/Immunology

BSc in Molecular Biology/Immunology

Outils

Flow cytometry

ELISA

Cytokine assays

Description du poste

King's College London invites applicants for a Postdoctoral Research Associate in the antibody discovery and immunotherapy program. The appointee will work on cancer immunology, antibody engineering, and ADC generation with translational aims toward first-in-man studies at Guy's Hospital.

You will perform functional assays, flow cytometry, NK cell interactions, and ex vivo organoid models, collaborating across teams led by Prof.