Pilot Plant Project Lead: GMP Changeovers & Optimization

ASTRAZENECA UK LIMITED; Macclesfield; On-site; GBP 50,000 - 70,000; Full time

Job summary

AstraZeneca UK Limited is seeking a Pilot Plant Project Co-ordinator to support safe, compliant manufacturing and cleaning activities in a dynamic pilot plant. You will coordinate plans, manage risks, and drive improvements across operations, engineering and quality functions.

The role requires a degree or equivalent technical experience, a data-driven mindset, and strong collaboration skills to ensure safety, quality and timely delivery of projects.

Qualifications

• A degree or equivalent experience in a scientific or engineering discipline.
• Technical or engineering capability gained in a relevant environment.
• A data-led approach to evaluating process performance and identifying improvement opportunities.

Responsibilities

• Co-ordinate activities supporting COMAH critical task analysis across operations and engineering.
• Plan and organise critical task assessments, involve key stakeholders and manage associated documentation.
• Maintain operational metrics and process safety performance information.
• Align operational and engineering plans, keeping stakeholders informed of progress, risks and priorities.
• Work with Campaign Managers/Technical Managers to plan and deliver product changeover cleaning activities.
• Lead improvement activities aimed at reducing changeover times.
• Co-ordinate the ordering and management of materials required for cleaning and, where appropriate, manufacturing.
• Prepare relevant SHE and GMP documentation to allow execution of manufacturing and cleaning activities.
• Collaborate with Process Engineers on relevant engineering change controls.
• Lead or support investigations, problem-solving activities and deviation management.
• Share learning and encourage consistent working practices across the pilot plant.
• A background in chemistry or chemical engineering would be particularly relevant, although we welcome applicants with equivalent experience from other scientific or engineering disciplines.
• Experience of structured problem-solving
• Project or business process management experience
• Practical experience within active pharmaceutical ingredient (API) manufacturing
• Knowledge or awareness of Good Manufacturing Practice and regulatory requirements

Skills

Data-driven

Project coordination

Communication skills

Collaboration

Safety & compliance

Education

Science or engineering degree

Job description

AstraZeneca UK Limited is seeking a Pilot Plant Project Co-ordinator to support safe, compliant manufacturing and cleaning activities in a dynamic pilot plant. You will coordinate plans, manage risks, and drive improvements across operations, engineering and quality functions.

The role requires a degree or equivalent technical experience, a data-driven mindset, and strong collaboration skills to ensure safety, quality and timely delivery of projects.