PhD: Predicting Combined Missense Effects in Proteins

University of Exeter; Exeter; On-site; GBP 20,000 - 24,000; Full time

Benefits offered by this job

Stipend and fees covered

Job summary

The University of Exeter invites applications for a PhD studentship to develop and validate a new variant effect predictor (VEP) capable of handling multiple missense changes within the same protein to aid clinical interpretation.

This interdisciplinary project combines in silico 3D protein structure modelling and machine learning with genetic, biochemical and functional datasets; supervision spans genetics, bioinformatics and protein structure, with funding from EPSRC.

Job description

The University of Exeter invites applications for a PhD studentship to develop and validate a new variant effect predictor (VEP) capable of handling multiple missense changes within the same protein to aid clinical interpretation.

This interdisciplinary project combines in silico 3D protein structure modelling and machine learning with genetic, biochemical and functional datasets; supervision spans genetics, bioinformatics and protein structure, with funding from EPSRC.