Funded PhD: Map Human Gene Interaction Networks with mVDA

University of Exeter; Exeter; On-site; GBP 20,000 - 24,000; Full time

Job summary

The University of Exeter invites applications for a funded PhD studentship focused on functional genomics and genetic interaction mapping using multiplexed Variable Dose Analysis (mVDA) in human cells.

The project integrates live-cell imaging, single-cell sequencing and computational analysis to map gene networks and identify potential combination therapies, with a strong emphasis on reproducible research and training across disciplines.

Responsibilities

• Adapt and optimise mVDA in human cells using established control interactions.
• Integrate this approach with live-cell imaging or single-cell sequencing depending on interest.
• Apply the platform as a proof-of-concept to investigate genetic interactions involving the tumour suppressor NF1.

Job description

The University of Exeter invites applications for a funded PhD studentship focused on functional genomics and genetic interaction mapping using multiplexed Variable Dose Analysis (mVDA) in human cells.

The project integrates live-cell imaging, single-cell sequencing and computational analysis to map gene networks and identify potential combination therapies, with a strong emphasis on reproducible research and training across disciplines.