Oligonucleotide Synthesis Team Lead | R&D Excellence

Randox Laboratories Ltd.; Crumlin; On-site; GBP 45,000 - 65,000; Full time

Job summary

Randox Laboratories Ltd. seeks an Oligonucleotide Synthesis Team Leader to drive the development, optimisation and implementation of synthesis purification and analysis methods.

You will lead a team of scientists, train staff, and maintain high-quality standards across synthesis, QC and collaboration with other departments. The role focuses on automated synthesis platforms, purification by HPLC/LCMS and thorough QC using LC-MS and capillary electrophoresis.

Qualifications

• Qualified to at least degree level in Chemistry, Biotechnology, Biochemistry or a life-science related subject.
• Strong analytical aptitude with an ability to work at the interface of chemistry and biology.
• Excellent communication and interpersonal skills.
• Be comfortable voicing opinions and sharing ideas with the rest of the team.
• Excellent organisation skills.
• High level of commitment and professional integrity.
• Experience in the development of new laboratory processes.

Responsibilities

• Leading, supporting and developing the oligonucleotide synthesis team.
• Training of team members in all aspects of synthesis work.
• Maintaining a high level of quality and safety within the team.
• Driving continuous improvement.
• Synthesis of oligonucleotides on automated platforms.
• Cleavage and deprotection of oligonucleotides following synthesis.
• Purification of oligonucleotides by various methods such as desalt, cartridge and HPLC.
• Quality assessments of synthesised oligonucleotides via LC-MS, HPLC and Capillary electrophoresis.
• Preparation of reagents and materials for synthesis, purification and QC.
• Contribute to the ongoing advancement of the lab including development and implementation of procedures.
• Troubleshoot synthesis and purification challenges to improve yield, quality and efficiency.
• Meet target timelines and deadlines.
• Cooperate and collaborate with other teams on various projects.

Skills

Team leadership

Communication

Analytical skills

Organisational skills

Integrity

Process development

Education

Degree in Chemistry or life sciences

Tools

LCMS

HPLC

Capillary electrophoresis

Oligonucleotide synthesizers

Job description

Randox Laboratories Ltd. seeks an Oligonucleotide Synthesis Team Leader to drive the development, optimisation and implementation of synthesis purification and analysis methods.

You will lead a team of scientists, train staff, and maintain high-quality standards across synthesis, QC and collaboration with other departments. The role focuses on automated synthesis platforms, purification by HPLC/LCMS and thorough QC using LC-MS and capillary electrophoresis.