International Lead Clinician (Botswana)

London School of Hygiene & Tropical Medicine; Greater London; On-site; GBP 50,000 - 82,000; Full time

Benefits offered by this job

Wellbeing days

Pension scheme

30 days annual leave (pro rata)

Job summary

The London School of Hygiene & Tropical Medicine is seeking a Clinical Research Fellow - International Lead Clinician to manage a multi-site trial across Botswana and other African sites. The role requires a medical degree with substantial trial experience and familiarity with HIV-related infections.

The post holder will be based in Gaborone full-time for recruitment, with frequent travel to partner sites. You will shape trial conduct, contribute to data analyses, and lead related sub-studies or

Qualifications

• Must hold a medical degree and have substantial clinical trial experience.
• Experience with HIV-related infections and cryptococcal meningitis is preferred.
• Strong data analysis and manuscript/report writing skills expected.

Responsibilities

• Oversee day-to-day operations of a multi-site phase IIb/III randomised trial.
• Coordinate trial activities across Botswana, Malawi, South Africa and Uganda.
• Lead data analysis, contribute to peer-reviewed publications, and develop related sub-studies.
• Travel to participating sites as required and manage trial coordination.

Skills

Clinical trials experience

HIV care & opportunistic infections

Public health research

Data analysis & interpretation

Education

Medical degree

Job description

Clinical Research Fellow - International Lead Clinician (Botswana)

Department Department of Clinical Research Salary £49,713 to £82,060per annum pro rata inclusive ClosingDate Monday 30 November 2026 Reference ITD-CRD-2026-26

The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.

LSHTM is seeking to appoint a Clinical Research Fellow - International Lead Clinician within the Department of Clinical Research. The post-holder will be responsible for the day to day running of a multi-site phase IIb into phase III randomised clinical trial of adjunctive interferon gamma for HIV-associated cryptococcal meningitis in Botswana, Malawi, South Africa and Uganda. They will work closely with the experienced senior trial management team, a trial manager and study coordinators at the participating African study sites. The applicant will be expected to be based full-time at the Trial Coordinating Centre in Gaborone, Botswana for the duration of the study recruitment and travel frequently to the other sites. The applicant will have the opportunity to work in a dynamic, international and supportive research environment and to shape the conduct of this clinical trial from the outset. They will also be expected to contribute to the data analysis and any peer-reviewed publication arising from the study, and to develop and lead related sub-studies or projects.

The successful candidate will hold a medical degree (clinicians from a variety of backgroundswill be considered) with a proven experience in the conduct of clinical trials or clinical research, ideally at senior level. They will have substantial clinical experience in the management of patients with HIV infection and opportunistic infections, including experience relevant to cryptococcal meningitis and clinical and research experience in resource-constrained healthcare settings in Africa. Further particulars are available in the job description.

The post is fixed term and full-time, 40 hours per week, 1.0 FTE. The post is funded for a period of 48 months and is available from 01 January 2027.

The salary will be in the range £47,551 to £78,898 per annum pro rata, or £67,325 to £77,348 per annum pro rata for eligible clinical academic doctors in higher specialty training (ST3 and above), depending on the applicable clinical academic salary scale and the successful candidate's circumstances. A Clinical Displacement Allowance of £2,162 per annum pro rata is payable where applicable.

The post will be subject to the LSHTM terms and conditions of service. Annual leave entitlement is 30 working days per year, pro rata for part-time staff. In addition to this there are discretionary "Wellbeing Days". Membership of the Pension Scheme is available. The post is based in Gaborone, Botswana.

The London School of Hygiene & Tropical Medicine is committed to being an equal opportunities employer. We believe that when people feel respected and included, they can be more creative, successful, and happier at work. While we have more work to do, we are committed to building an inclusive workplace, a community that everyone feels a part of, which is safe, respectful, supportive and enables all to reach their full potential.