Global Clinical Trial Manager — Phase I–IV Leadership

Discover International; Park Central; On-site; GBP 65,000 - 90,000; Full time

Job summary

Discover International is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors. You will manage cross-functional teams and drive study timelines from start-up through close-out.

The role requires a life sciences degree and 4+ years in clinical trial management, with strong knowledge of ICH-GCP and UK/EU regulations. You will mentor junior staff and ensure sponsor communication throughout the trial lifecycle.

Qualifications

• Life sciences degree (or equivalent experience).
• 4+ years in clinical trial management within a CRO, pharma, or biotech setting.
• Proven line management/mentoring experience.
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring.
• Experience in oncology, rare disease, or cardiovascular trials.

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards.
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance.
• Serve as primary point of contact for sponsors, providing status updates and risk escalation.
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans.
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs.
• Lead site selection, feasibility assessments, and study start-up activities.
• Chair internal and sponsor study team meetings.

Skills

Clinical trial management

Team leadership

Budget & vendor oversight

Risk-based monitoring

Sponsor communication

Education

Life sciences degree

Job description

Discover International is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors. You will manage cross-functional teams and drive study timelines from start-up through close-out.

The role requires a life sciences degree and 4+ years in clinical trial management, with strong knowledge of ICH-GCP and UK/EU regulations. You will mentor junior staff and ensure sponsor communication throughout the trial lifecycle.