Global Clinical Trial Manager (Phase I–IV)

Discover International; Watford; On-site; GBP 65,000 - 90,000; Full time

Job summary

Discover International, a UK-based CRO, seeks a Clinical Trial Manager to lead operational delivery of Phase I–IV trials, coordinating cross-functional teams and sponsor communications from start-up to close-out.

The role requires a life sciences degree and 4+ years in trial management, with strong ICH-GCP knowledge, budget and vendor oversight, and experience in oncology, rare disease, or cardiovascular programs.

Qualifications

• Life sciences degree or equivalent required.
• Min 4+ years in clinical trial management within CRO, pharma or biotech.
• Proven line management experience.
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring.
• Experience managing study budgets and vendors.
• Experience in oncology, rare disease, or cardiovascular trials.

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards.
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance.
• Serve as primary point of contact for sponsors, providing status updates and risk escalation.
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans.
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs.
• Lead site selection, feasibility assessments, and study start-up activities.
• Chair internal and sponsor study team meetings.

Skills

Line management

Cross-functional collaboration

Risk management

Sponsor communication

Education

Life sciences degree or equivalent

Job description

Discover International, a UK-based CRO, seeks a Clinical Trial Manager to lead operational delivery of Phase I–IV trials, coordinating cross-functional teams and sponsor communications from start-up to close-out.

The role requires a life sciences degree and 4+ years in trial management, with strong ICH-GCP knowledge, budget and vendor oversight, and experience in oncology, rare disease, or cardiovascular programs.