Global Clinical Trial Manager – End-to-End Trials

Discover International; Warrington; On-site; GBP 65,000 - 90,000; Full time

Job summary

Discover International, based in the United Kingdom, seeks a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors, coordinating cross-functional teams from start-up through close-out.

You will own end-to-end trial management, oversee budgets and vendors, supervise CRAs/CRCs, provide sponsor updates, and ensure inspection readiness under ICH-GCP and UK/EU regulations.

Qualifications

• Life sciences degree (or equivalent experience)
• 4+ years in clinical trial management within a CRO, pharma, or biotech setting
• Proven line management/mentoring experience
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring
• Experience managing study budgets and vendors
• Experience in oncology, rare disease, or cardiovascular trials

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance
• Serve as primary point of contact for sponsors, providing status updates and risk escalation
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs
• Lead site selection, feasibility assessments, and study start-up activities
• Chair internal and sponsor study team meetings

Skills

Line management/mentoring

ICH-GCP knowledge

Trial regulations (UK/EU)

Budget & vendor management

Risk-based monitoring

Oncology/rare disease/cardiovascular

Education

Life sciences degree

Job description

Discover International, based in the United Kingdom, seeks a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors, coordinating cross-functional teams from start-up through close-out.

You will own end-to-end trial management, oversee budgets and vendors, supervise CRAs/CRCs, provide sponsor updates, and ensure inspection readiness under ICH-GCP and UK/EU regulations.