Global Clinical Trial Manager - End-to-End Study Delivery

Discover International; Slough; On-site; GBP 70,000 - 100,000; Full time

Job summary

Discover International, partnered with a UK-based CRO, is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors, guiding cross-functional teams from start-up to close-out.

You will own end-to-end trial management, line-manage CRAs/CRCs, handle sponsor updates and risk, and ensure compliance with ICH-GCP, MHRA, and sponsor SOPs, while driving timelines, budgets and vendor oversight.

Qualifications

• Degree in life sciences or equivalent required.
• At least 4 years in clinical trial management in CRO/pharma/biotech.
• Proven line management or mentoring experience.
• Solid knowledge of ICH-GCP, UK/EU regulations, risk-based monitoring.
• Experience with budgets and vendor management.

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring on-time delivery.
• Line-manage CRAs/CRCs and oversee site monitoring plans.
• Serve as primary sponsor contact, providing status updates and risk escalation.
• Develop and manage study budgets, timelines, and vendor oversight.
• Ensure inspection readiness and compliance with sponsor SOPs.
• Lead site selection, feasibility assessments, and startup activities.
• Chair internal and sponsor study team meetings.

Skills

Line management

Budget management

Stakeholder communication

Regulatory knowledge

Risk-based monitoring

Vendor management

Education

Life sciences degree

Job description

Discover International, partnered with a UK-based CRO, is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors, guiding cross-functional teams from start-up to close-out.

You will own end-to-end trial management, line-manage CRAs/CRCs, handle sponsor updates and risk, and ensure compliance with ICH-GCP, MHRA, and sponsor SOPs, while driving timelines, budgets and vendor oversight.