Clinical Trial Manager - Lead End-to-End Phase I–IV Trials

Discover International; England; On-site; GBP 60,000 - 90,000; Full time

Benefits offered by this job

Health insurance

Job summary

Discover International, in partnership with a UK-based CRO, is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors. You will manage cross-functional teams and study timelines from start-up through close-out.

You will own end-to-end trial management, line-manage CRAs/CRCs, handle sponsor communications, budgets and vendor oversight, and ensure inspection readiness with ICH-GCP and MHRA compliance.

Qualifications

• 4+ years in clinical trial management within a CRO, pharma, or biotech setting.
• Line management/mentoring experience.
• Strong knowledge of ICH-GCP, UK/EU trial regulations, and risk-based monitoring.
• Experience managing study budgets and vendors.
• Experience in oncology, rare disease, or cardiovascular trials.

Responsibilities

• Own end-to-end trial management for assigned studies, ensuring delivery on time, on budget, and to quality standards
• Line-manage CRAs/CRCs, overseeing site monitoring plans and performance
• Serve as primary point of contact for sponsors, providing status updates and risk escalation
• Develop and manage study budgets, timelines, and vendor/CRO oversight plans
• Ensure inspection readiness and compliance with ICH-GCP, MHRA, and sponsor SOPs
• Lead site selection, feasibility assessments, and study start-up activities
• Chair internal and sponsor study team meetings

Skills

Clinical trial management

Line management

Sponsor communication

Budget management

ICH-GCP knowledge

Education

Life sciences degree

Equivalent experience

Job description

Discover International, in partnership with a UK-based CRO, is seeking a Clinical Trial Manager to lead the operational delivery of Phase I–IV trials for pharmaceutical and biotech sponsors. You will manage cross-functional teams and study timelines from start-up through close-out.

You will own end-to-end trial management, line-manage CRAs/CRCs, handle sponsor communications, budgets and vendor oversight, and ensure inspection readiness with ICH-GCP and MHRA compliance.